Ask Tufts Experts

I was interested in your Q&A about fruit juices affecting medi- cations (April). What about tomato juice?

I have read that eggs from free-range chick-ens have less cholesterol than from chickens confined in pens. Is this true?

What are the benefits or cons of bee pollen and natural honey?

I am a subscriber who is a mild diabetic. My wife serves grape tomatoes at dinner, which are much tastier than regular tomatoes this time of year. I would like your input on the sugar content and nutritional difference between grape and regular tomatoes.

Is it true that research has shown that drinking diet drinks can cause weight gain? Do you recommend that someone wishing to lose weight (or anyone else) should avoid them?

Can levels of the “good” HDL cholesterol be too high?

I am living alone and very often make a little too much food for one meal. I am wondering if much nutrition is lost when I reheat a veggie for a second night, which I often do.

Are green bananas safe to eat? Are they as good for you as ripe bananas?

I have wondered why sea salt is so often touted in recipes. Considering that our sea waters are so contaminated now, is there no concern that their condensed form, salt, could be harmful to ingest?

I bake some favorite desserts and recently switched to wholewheat pastry flour. Is whole-wheat pastry flour as nutritious as regular wholewheat flour?

I was interested in your article about oranges (January 2010), but I remember reading that when I take Cipro I should be careful of when I drink orange juice. Is this right?

Do clementines have the same nutritive value as oranges?

You often report about research on “processed” meats. But what exactly does “processed” meat mean?

Is sauerkraut anticarcinogenic?

I enjoyed your Special Report on “Food and Your Mood” (January 2010), but wanted to know more about serotonin. Is it true that eating foods high in tryptophan boosts serotonin levels? What about supplements sold as “mood enhancers” that are related to tryptophan?

Since calcium and vitamin D strengthen bones and vitamin A weakens bones, why is all reducedfat milk fortified with both vitamin A and vitamin D? And why is whole milk not?

I have read that pomegranate juice interferes with the availability and absorption of hypertension medication, in much the manner that grapefruit juice does. Is this true? If so, is the effect diminished by taking the juice hours before or after the medication?

I’ve often read in your newsletter that all fats contain about 120 calories per tablespoon. So why does my butter package say a tablespoon contains only 100 calories?

I have osteoporosis, and my doctor wants me to take 1,000 IU daily of vitamin D, along with my other daily vitamins, which also contain vitamin D. I calculate that this would bring my daily vitamin D total to 2,300 IU. Is this safe?

I’ve noticed that some cereals contain freezedried fruit. How does freeze-dried compare to fresh fruit in terms of nutrition?

Given the recent reports about bacterial contamination in nuts, does it make sense to heat nuts to a certain temperature before eating? This works for eggs and meat, why not nuts?

A friend in India claims that it is not advisable to eat fruit at the end of a meal, because the nutritional value of the fruit is diluted when it comes on top of other food. Is there any truth to this?

After getting so many different answers, can you please tell me how bad is aspartame? I like chewing gum sweetened with it—two or three pieces a day— and people tell me I should cut down because aspartame is bad.

Besides being kosher for religious purposes, what’s the difference between kosher salt and other salt?

Is it contraindicated for individuals at risk of developing calcium oxalate kidney stones to take vitamin D3 supplements?

In your May issue you illustrated the “radura” sign for food treated by irradiation. A caterer told me all pork is irradiated to prevent trichinosis; that is why it can be served when the meat is still pink inside. However, pork sold in grocery stores does not have this sign on it. Is it true that pork is safe to eat when cooked this way? I was taught to cook pork until it was gray inside.

I have long read recommendations of low-fat milk. How about powdered milk? I have used it for about 50 years—mixed extra rich—for the vitamin D, calcium and no fat.

I take a multivitamin with my morning cup of tea. Do I need to be worried that the tea might block the absorption of the vitamins?

I take supplements of vitamin B12 daily, plus a “mature” multivitamin containing vitaminB12. Should I be worried about the risk of overdosing on vitamin B12?

We’ve read that drinking a lot of fruit juice or eating a lot of turmeric or blueberries can help prevent Alzheimer’s. But isn’t it futile after 50 or 60 years to try this? Wouldn’t it take a lifetime of eating these foods to do any good? At what age approximately does it really not make any difference?

Your March 2009 newsletter discusses obesity, as measured by Body Mass Index (BMI). Would you please advise how to calculate BMI?

I’ve heard that California almonds are being irradiated. Does this mean that these almonds no longer have any nutritional value? Are they harmful to eat?

QI’ve read that wild blueberries are good for you, but most of us have access only to cultivated berries. Does this mean that cultivated berries are not as good for you?

QI like fresh salmon, but it’s too expensive so I buy canned salmon. Is canned salmon as nutritious as fresh?

QI am confused by whether shrimp and other shellfish are good in the diet due to attributes such as being high in protein, low in fat and low in calories, or bad because they are high in cholesterol. Please clarify.

QBack in the 1950s, Carlton Fredericks, a popular radio personality, touted the virtues of blackstrap molasses. Mom bought some for Dad, but after one taste it was history. About a year ago, though, I ran across it in the store and was amazed that it appears to be a “superfood.” Why have you never mentioned blackstrap molasses in your newsletter?

I know that 100% whole-wheat bread is better for you than white bread. But how nutritious are breads such as rye and pumpernickel?

I enjoy eating buffalo meat when I am able to buy it from local farmers. It’s very lean, but is it more healthful than regular beef in other ways?

Do egg yolks really differ from egg whites in terms of raising “bad” (LDL) cholesterol? What’s a safe weekly limit for both parts of the egg?

I know it can be harmful to eat charred, blackened meat. Is the same true of overtoasted nuts, burnt potatoes and the like?

How does microwaving affect the nutritional value of food?

I take flax-oil supplements every day and I was alarmed to read in your September 2008 issue that high intake of alpha-linolenic acid (ALA), found in flax, was actually associated with an increase in risk for early age-related macular degeneration (AMD). Should I stop taking flax oil?

Is buckwheat a grain or is it actually a seed? I have it for breakfast every morning, and am wondering if I’m getting all the benefits one gets from grains.

How can I keep from overeating during the holidays?

Your newsletter often states the advantages of omega-3 fatty acids. But how much fish should I consume to benefit?

With the increasing evidence for the benefits of vitamin D, is there any artificial light that will give me the benefits of sunshine in making vitamin D?

My doctor has prescribed me Coumadin (warfarin) to fight blood clots. I see that you’re supposed to avoid foods that contain “large amounts” of vitamin K when taking warfarin. Can you offer any more specific guidance as to what “large amounts” means?

Dr. Dean Ornish claims that olive oil reduces blood flow by 31%. Is this true and if so is it a reason to stop using olive oil?

Is frozen yogurt as nutritious as regular yogurt? What happens to live cultures such as acidophilus when yogurt is frozen?

What can you tell me about the possible toxic effect of peanut oil lectin (PNA)? I’ve read where the “Paleo Diet” cites research showing that PNA from peanuts and peanut oil clogs the arteries.

When nutritionists talk about walnuts, do they mean black or English walnuts?

We live in southern Arizona where citrus trees thrive and own two well-producing grapefruit trees. Are there prescription drugs that do not act well with grapefruit?

My eczema has become worse over the last few years. Are there any foods that I should avoid?

How does tapioca rate nutritionally? Does it fall under the refined food category? I like to use it to make tapioca pudding with Splenda and nonfat Lactaid milk and eat about one cup of the pudding as a dessert twice a day. Should I cut back?

I read a report recently indicating that all nuts contain monosaturated fat. I thought this was true only of almonds, and that the rest contain polyunsaturated fat. Am I wrong?

Is much of the omega-3 lost when the skin of the salmon is discarded?

I have been told that the sugar substitute Splenda is unhealthy due to the chemicals used to process sugar into Splenda. Can you clarify?

I am enclosing an article from a local newspaper warning people to avoid eating any fish ever (“Thinking Twice About Tuna” by Bruce Friedrich of the People for the Ethical Treatment of Animals, Palo Alto Daily News). I would like to know whether this very alarmist article has any basis in fact.

You mention “Body Mass Index” (BMI), but instead of explaining how to calculate it you refer to a Web site. How can I calculate BMI without a computer?

In your May “Ask Tufts Experts,” you compared the nutrition in white potatoes, sweet potatoes and yams. But I’m confused about the difference between sweet potatoes and yams?

Your Special Report on aspartame and high-fructose corn syrup (September Healthletter) made me wonder about ordinary table sugar. How does it compare to fructose in terms of calories? And if I want to cut calories but am still concerned about aspartame, what are my options?

In your June 2007 newsletter you reported the recommended AREDS antioxidants combination to reduce the risk of macular degeneration. It included copper. Recently, on a TV program, I heard a doctor warning against using copper as part of a multivitamin intake, stating that copper was bad for your health. It would be reassuring reading your opinion on this. If copper is to be used, in what amounts?

I enjoy Indian food very much and it appears very healthy, with many vegetables that are tasty and interesting. But most Indian recipes are made with clarified butter or “ghee.” I imagine this is not very beneficial from the point of view of fat and atherosclerosis, but I may be wrong. Could you explain and give your opinion?

I keep reading that adding milk to tea interferes with its antioxidant activity. How about soy milk?

Is there any relationship between blood type and nutrition? Are certain foods detrimental to some blood types and excellent for other blood types?

In your August newsletter it is stated that we should not fry fish. My wife says you are talking about battered fish or shrimp that is deep-fried, such as fish sticks or fast-food fish sandwiches. She says it’s OK to “fry” fish such as plain Tilapia in a tablespoon of olive oil in a skillet on the stove top. I say that your article means neither deep frying nor skillet frying should be done. Who’s right?

In your July newsletter, you indicated that whole grain consists of bran, germ and endosperm. For years I have been purchasing wheat germ and wheat bran and using a heaping tablespoon of each in a liquid mixture at breakfast and dinner. From your article I gather that I am failing to consume a whole grain product. Is the endosperm essential? Do I need to change this consumption pattern?

Everyone is singing the praises of fish oil nowadays, but I read that it raises your LDL bad) cholesterol? Is that true? so, what is the alternative?

What is the recommend daily dose of folate? Is there an upper limit?

At our local supermarkets a fish called “steelhead trout” is sold. The flesh is pinkish like salmon, not like trout. What exactly is this fish and is it a good source of omega-3?

In your April issue on “Eating for Endurance,” you state that plant proteins are incomplete proteins with the exception of soy protein. I thought quinoa supplied all the essential amino acids. Isn’t quinoa a complete protein grain?

Is there a chart of daily food allowances for people over 80 years old?

Does regular exercising enlarge one’s lipid particles (HDL, LDL and VLDL), which is supposed to be beneficial to one’s health?

I have seen many emails and Web postings about people getting sick from the artificial sweetener aspartame. I am a diet cola consumer, so I wonder: Is aspartame dangerous?

I’ve read that calcium should be taken/ingested periodically during the day, as only a certain amount is absorbed at once. Please tell me if this is important and, if so, how much is advisable to take and at what intervals?

Is canned spinach just as good as fresh spinach to protect my vision?

We always have a bounty of fresh fruit—more than we can eat before it goes bad. Is it possible to freeze fresh fruit without adding sugar?

What’s the safe level of daily vitamin D? Is it different for older people? Also, I take fish-oil pills each day as recommended by my heart specialist, as well as a vitamin D supplement, and I’m worried that I may be getting too much vitamin D. How much vitamin D is found in fish-oil pills if any?

I have been hearing about cinnamon as a “cure” or at least a treatment for diabetes. As a patient with medically controlled type 2 diabetes, I am naturally interested. Anything to it?

I have been told that using olive oil for cooking causes the oil to hydrogenate and is therefore unhealthy. Would you please address this?

Do you know anything about a substance called “714X” that has been used in the treatment of cancer? My cousin told me she heard something about it on TV. Where can I find out more about it and its use?

I understand that Concord grapes are high in nutritional value. Because I don’t see this variety in local super markets, do other red grapes have similar nutritional value?

Which is “fresher”— vegetables canned soon after harvesting, frozen or so-called “fresh” as pawed over by the public or in plastic?

As a vegetarian, I am interested in the combination of fruits and vegetables that will provide a complete set of essential amino acids in sufficient quantities. Can you help?

Is it safe to eat the mold that forms on cheese? I tend to throw it out, but wonder if there are cheeses that have desirable molds.

What’s the difference between whole-wheat pastry flour and regular whole-wheat flour?

I usually agree with most of your articles, but I think you dropped the ball on your “51 Healthy Foods” (August) concerning peanut butter. You did not specify the peanut butter should be “natural.” Most others have hydrogenated trans fat and you know that is harmful.

In your list of “51 Healthy Foods,” you list carrots but do not say cooked or raw. It is my impression that the human system cannot digest raw carrots because the cellulose walls are resistant. Is this correct?

For the lactose intolerant, does soy milk offer as much calcium benefit as cow’s milk?

I make smoothies using only fresh squeezed OJ, yogurt and fresh or frozen fruit (mostly bananas and berries). Is the fiber in the fruit lost by blending them into the smoothie? What about other vitamins and minerals?

Is there a difference in the effect on the body between natural (l-alpha tocopherol) and synthetic (d,ltocopherol) vitamin E?

Can you compare the nutritional value of sweet potatoes/ yams with white Idaho baking potatoes? What about fiber content? Sweet potatoes seem to contain more fibrous material, but such impressions can be misleading.

I understand how to identify trans fats as “partially hydrogenated.” But I sometimes see “fully hydrogenated” —for example, on Reduced Fat Jif Peanut Butter. Can you please explain what “fully hydrogenated” means and what, if any, impact it has on our health?

The new federal dietary guidelines call for at least two servings of fish a week. At this time of year, the only fish available in my grocery store is farm-raised. I have also read that you should limit your consumption of farm-raised fish to two times a month. What should I do?

I recently read that one shouldn’t microwave food in plastic containers because carcinogens are released into the food. Does this apply to all plastic containers, even those specifically designed for microwaving?

Do dried sweetened cranberries contain vitamin C ?

Xango is a liquid fruit product made from mangosteen and other fruits. Are there any human studies indicating that mangosteen fruit, containing xanthones, is useful in human health?

What is the latest health information on Krill Oil? I hear good things about Krill Oil as a good source of omega-3, omega-6 oils and astaxanthin.

I have heard that decaffeinated coffee promotes arthritis. Is this true?

I have read that when buying bread and cereals, one should look for “whole grain” on the package, not just “whole wheat.” Is whole grain better than whole wheat or are they the same thing?

I have a tendency toward high potassium. Can you recommend foods to avoid?

In the January 2005 article “Remember to Drink Your Tea,” it was not mentioned if research was on regular or decaffeinated tea. I’m interested, as we drink decaf.

Often you extol the virtues of canola and olive oils, but grapeseed oil is never mentioned. I have read that it lowers LDL and raises HDL—unlike any other oils available. It has less saturated fat than other commonly used oils. Since you never mention it, though, I wonder if there are negative health aspects that I should be aware of?

In your January issue you state that “yogurt, while a good source of calcium, doesn’t deliver the vitamin D benefit that milk does.” This has me puzzled. I make yogurt regularly from skim milk with added dry milk, both of which have added vitamin D. Why would the yogurt not deliver the vitamin D benefit that milk does?

In your article on organics (October 2006 Healthletter) you make note that seafood has not met “Certified Organic” guidelines as of yet. Enclosed you will see that I have purchased fish from Ecuador that meets these standards. What is the legitimacy of this product?

I read of a German study on alpha-lipoic acid for treating Alzheimer’s. Would it be a good idea for my husband and me (we’re in our 60s) to take alpha-lipoic acid as a preventative measure?

I love shredded coconut, but I’ve heard that it contains saturated fat. I thought only animal products had saturated fat?.

Frankly, I’m getting real tired of being told I don’t know what I’m talking about. My husband and I both have high cholesterol. My husband is a hunter, and he and his buddies claim that wild meat is good and OK to eat as much as one wants. I say red meat is red meat regardless. If I’m wrong, fine, I’ll accept it; if not, then they will be stuck with more chicken, fish or turkey dishes.

I received a mailing that claimed colon build-up is “the real cause of 90 percent of all diseases.” Is this true? Is colon cleansing good for you?

I am excited about more lutein from chicken eggs (NewsBites, Nov. 2004). Where do they have lutein-fed chickens? Where do we buy the eggs?

I have heard that the greatest nutritional value of the apple is in the skin. In making applesauce by cooking the apples with their skins on, do the vitamins and other nutrients remain in the sauce?

My son-in-law is troubled with arthritis in his hands. My daughter read “somewhere” that eating cherries might alleviate the problem. Is there any evidence that eating cherries or drinking cherry juice will help against arthritis?

I recently read an article on “Modified Citrus Pectin” (MCP) and its possible effectiveness in fighting cancer. What can you tell me about MCP?

A friend recently suggested I take Greens First, which claims to have the “antioxidant power of over 10 servings of fruits and vegetables in every scoop.” Have any tests been reported indicating that such a product would really be as effective an antioxidant as 10 servings? Is there any evidence that fruits and vegetables “juiced and then spray-dried at low temperature” are as beneficial as or almost as good as the fruits and vegetables themselves?

Should I be using hand-sanitizing products to help prevent the flu?

In your November article on the “Mediterranean Diet,” you describe it as “low in meat, dairy products and polyunsaturated fat.” Do you really mean to avoid polyunsaturated fat? I though this was one of the good fats.

I have heard that high heat destroys the healthy fats in nut oils; so, for example, it would not be a good idea to use walnut oil in a skillet. If I roast any kind of nuts in the oven, does that also harm the oils in them, or is there a temperature limit that is OK?

I read the article “How Safe Are Your Salad Greens?” (December 2006 Healthletter) with great interest. Will washing fruits and vegetables in vinegar and water kill E. coli? If so, how much vinegar to water should be used?

A local specialtyfood store was passing out an article about canola oil that says canola oil is an industrial oil, genetically engineered rapeseed, and “deadly for the human body.” Should I stop using canola oil?

I’ve heard a lot about arthritis sufferers consuming ginger to reduce inflammation and relieve pain. What are the latest research findings about ginger?

In your November 2007 issue, you said that experts prescribe strength training for seniors at least once a week. What equipment and exercises are recommended for a healthy senior to build and maintain muscles?

 
 
 

I was interested in your Q&A about fruit juices affecting medi- cations (April). What about tomato juice?

Answer :  We checked in again with David G. Bailey, PhD, a professor of clinical phar-macology at Western Ontario University, who found that fruit juices (including orange, apple and grapefruit) consumed within two hours of taking certain medications dramati-cally weakened the drugs’ effectiveness. Bailey and colleagues did not test tomato juice spe-cifically, but he says, “Fruits and vegetables contain a lot of flavonoids. We have been able to show that one of the important active in-gredients in grapefruit juice is naringin, which is a flavonoid. Thus, it is possible, but not yet shown, that another member of this family would also impair the absorption of certain drugs. Naringin is not found in tomato juice, however. Based on our current understanding, I would suggest that the way to get the most reliable effect is to take medications with a glass of water on an empty stomach at least two hours before eating, if possible

I have read that eggs from free-range chick-ens have less cholesterol than from chickens confined in pens. Is this true?

Answer :  

Given the growing popularity of “free-range” chickens, surprisingly little scientific research has been done on the nutritional differences, if any, of these chick-ens or their eggs compared to chickens raised in more confined conditions. A 2007 study conducted by Mother Earth News magazine, but not published in a peer-reviewed scientific journal, did find that eggs from free-range chickens contained one-third less dietary cholesterol and (more important for blood cho-lesterol levels such as LDL) one-quarter less saturated fat. The eggs from free-range birds were significantly higher in vitamin A, vitamin E and beta-carotene and contained twic omega-3 fatty acids.

Several other studies have shown that free-range eggs are superior in one or another nutrient, but few have produced similar results regarding cholesterol and saturated fat. A 1999 Penn State University study did report that eggs from free-range (or “pastured”) birds had 10% less total fat and 34% less dietary cholesterol compared to the standard USDA data on supermarket eggs. (The same study also tested free-range chicken meat, and found it to have 30% less saturated fat than the USDA standard.)

The American Egg Board, which repre-sents the conventional egg industry, maintains that “the nutrient content of eggs is not af-fected by whether hens are raised free-range or in floor or cage operations.” The industry’s Egg Nutrition Council says, “Barring special diets or breeds, egg nutrients are most likely similar for egg-laying hens, no matter how they are raised.”

What are the benefits or cons of bee pollen and natural honey?

Answer :  

For a quick sense of the commercial versus scientific status of these popular products, compare the results of a Google search for “bee pollen health benefits”—over 80,000 hits— to those of a similar search of the government’s exhaustive PubMed database of medical research: 121 results, most of only peripheral relevance to human health. “Bee pollen” is actually a misnomer: It’s simply the pollen from flowers that bees collect and bring back to the hive. “Natural” or “raw” honey may contain resins from propolis, a sort of “bee glue” also touted for health benefits.

For centuries, various bee products have been touted as aiding athletic and sexual performance, fighting infections, preventing cancer and promoting both weight loss and weight gain. The Federal Trade Commission has frequently cracked down on vendors of bee pollen and similar products for unsubstantiated claims ranging from treating allergies to arthritis, fatigue to arteriosclerosis.

A handful of studies have suggested that bee pollen may have some benefit against chronic prostatitis (a disease of the prostate) and menopausal symptoms, and that propolis may help dental hypersensitivity and possess antibacterial effects. A few studies have found “natural” honey superior to processed honey in cholesterol and blood-sugar effects. Honey— “natural” or otherwise—has been studied for blood-sugar control and insulin sensitivity (versus other sweeteners), as a cough suppressant and as an immune-system booster. None of the evidence for any of these claims is strong enough to support the use of any bee-related products for health reasons alone. If you like a little honey in your tea, that’s fine—but keep in mind that you’re adding about 20 calories per teaspoon.

Potential downsides to bee products include the possibility of dangerous allergic reactions and potential contaminants ranging from heavy metals to pesticides. Bee pollen has been linked to liver damage in isolated cases. And children younger than 12 months should never be fed any kind of honey because of the risk of infant botulism.

I am a subscriber who is a mild diabetic. My wife serves grape tomatoes at dinner, which are much tastier than regular tomatoes this time of year. I would like your input on the sugar content and nutritional difference between grape and regular tomatoes.

Answer :  

Overall, the nutritional differences between types of tomatoes—including grape, cherry and other bite-sized varieties, as well as plum, Roma and other larger options—are quite small, probably less than the variations by season and producer within any one type. We checked with two leading producers of grape tomatoes and got slightly different nutritional data. In general, though, grape tomatoes are similar to regular tomatoes in calories, carbohydrates, dietary fiber and sugar content. Both grape and regular tomatoes supply about 25% of your daily vitamin A and 32% of daily vitamin C. A cup of either grape or regular tomatoes has a glycemic load (see story on page 1) of about 2, so neither choice will significantly raise blood sugar. It may be that the grape tomatoes you’re enjoying have a higher sugar content and sweeter taste than the currently available regular tomatoes—but not necessarily different from regular tomatoes found later in the season.

One difference noted in 2002 research in the Journal of Agricultural and Food Chemistry is that cherry tomatoes have higher levels of antioxidants than normal-sized tomatoes; this would likely also be true for the similar “grape” tomatoes. The research also reported that riper cherry tomatoes have higher levels of carotenoids and antioxidants than those picked when less ripe.

Is it true that research has shown that drinking diet drinks can cause weight gain? Do you recommend that someone wishing to lose weight (or anyone else) should avoid them?

Answer :  Susan B. Roberts, PhD, director of Tufts’ HNRCA Energy Metabolism Laboratory and author of The I Diet , replies: “My clinical observation is that for some people they help and for others they don’t. It depends on how you use them. If they are a substitute for with-sugar drinks and over time you look on them as a bridge to a low-sugar and low-sweet diet, that is a great way to go in my opinion! Weight loss is hard for many people and you need to use all the help you can.”

Can levels of the “good” HDL cholesterol be too high?

Answer :  Alice H. Lichtenstein, DSc, director of Tufts’ HNRCA Cardiovascular Nutrition Laboratory, replies, “To my knowledge, there are no data to indicate that HDL can be too high.” The National Heart, Lung and Blood Institute’s (NHLBI) National Choles terol Education Program recommends HDL levels of 60 mg/dL or greater for protection against cardiovascular disease.

I am living alone and very often make a little too much food for one meal. I am wondering if much nutrition is lost when I reheat a veggie for a second night, which I often do.

Answer :  Alice H. Lichtenstein, DSc, director of Tufts’ HNRCA Cardiovascular Nutrition Laboratory, says that microwaving or gentle reheating in a pan shouldn’t do much damage to the nutrients in previously cooked vegetables. (This is another good reason, though, not to overcook vegetables the first time—they’ll stand up better to reheating.) Another option she suggests is to add cold cooked veggies to perk up a salad.

Are green bananas safe to eat? Are they as good for you as ripe bananas?

Answer :  Contrary to popular belief, eating green bananas won’t make you sick (unless, of course, as with other foods, you eat too many of them), though they may be more difficult to digest than the ripe fruit. Fully ripened bananas may have developed slightly more antioxidants, but otherwise the nutritional profiles of green and ripe bananas are quite similar. In fact, green bananas might have a few advantages: As bananas ripen, they convert starches into sugars, so greener fruit are less sweet and affect your blood sugar less. Green bananas also contain more short-chain fatty acids (SCFAs), which are indigestible to humans but nourishing to the cells that line your intestines. Various studies have shown improvements in intestinal function from consuming SCFAs in general and green bananas in particular.

I have wondered why sea salt is so often touted in recipes. Considering that our sea waters are so contaminated now, is there no concern that their condensed form, salt, could be harmful to ingest?

Answer :  

Unlike regular table salt, which is mined from rock salt, “sea salt” is produced by the evaporation of seawater. The concentrated brine precipitates the salt, which is then gathered by harvesting machines. Both types of salt (as well as “kosher salt,” which can be mined or evaporated from seawater) consist of sodium chloride, although sea salt may also contain trace amounts of other minerals that— adherents say—give it a different taste. Sea salt typically does not contain added iodine, which helps prevent goiter. Some purveyors of “purified” or “synthetic” sea salt do warn that other brands could contain mercury and other contaminants; they point out that the waters off Brittany, in northwestern France, which produce much of the sea salt popularly sold as “natural,” are badly polluted. The FDA has not issued any warnings about adverse health effects from contaminated sea salt, however, and in any case it’s unlikely that you’d consume enough to ingest much pollutants. We also note that the Environmental Defense Fund, which among other things monitors and advocates for the purity of the world’s oceans, doesn’t hesitate to call for sea salt in recipes on its web site www.edf.org.

Sea salt can be either fine (similar to table salt) or coarse (like kosher salt). Because the larger grains don’t pack as tightly together, a quarter-teaspoon of coarse sea salt contains 570 milligrams of sodium, compared to 590 milligrams in the same volume of table salt (and 480 milligrams in kosher salt).

I bake some favorite desserts and recently switched to wholewheat pastry flour. Is whole-wheat pastry flour as nutritious as regular wholewheat flour?

Answer :  So-called “pastry flour,” also known as Graham flour, is milled from soft wheat that’s lower in protein than regular wheat. The resulting flour weighs less than standard whole-wheat flour—it takes 1/3 cup to weigh 30 grams, compared to 1/4 cup of the same manufacturer’s non-pastry whole-wheat flour—and has slightly fewer calories by weight (100 in 30 grams, versus 110). Besides being lower in protein (3 grams per serving versus 4) and therefore lower in gluten, whole-wheat pastry flour is similarly lower in fiber (3 grams instead of 4). Despite these small nutritional differences, whole-wheat pastry flour is still a better choice for cookies, pie crusts and hearty cakes than all-purpose or cake flour made from refined wheat.

I was interested in your article about oranges (January 2010), but I remember reading that when I take Cipro I should be careful of when I drink orange juice. Is this right?

Answer :  It’s commonly known that grapefruit juice has the potential to boost excessively the action of many prescription drugs. David G. Bailey, PhD, a professor of clinical pharmacology at Western Ontario University who discovered that grapefruit-drug interaction 20 years ago, recently identified a reverse effect of some common juices—including orange, apple and, again, grapefruit juice. The mechanism is different from that by which grapefruit can overly enhance the power of drugs (through deactivating a gastrointestinal enzyme that normally breaks down medications before absorption into the bloodstream). In research presented to the American Chemical Society in 2008, Bailey and colleagues reported that fruit juices consumed within two hours of taking certain other medications can decrease their absorption sufficiently to raise concern for weakened effectiveness. Currently identified medicines negatively affected include blood-pressure-lowering beta blockers (such as atenolol, celiprolol and talinolol), the allergy treatment medication fexofenadine, the antibiotic ciprofloxacin and the anti-cancer drug etoposide. Researchers believe naringin, the compound that gives grapefruit its bitter taste, is responsible for a major portion of the effect in grapefruit juice, and have identified a naringin-like chemical in orange juice as well. The findings don’t mean you have to give up fruit juice, however. Juice consumed four hours prior to taking medications had no weakening effect. Bailey advises, “Take your medications with water, at least two hours before consuming fruit juices or eating fruit, if possible on an empty stomach, to prevent reduced drug absorption.”

Do clementines have the same nutritive value as oranges?

Answer :  Although sometimes called “seedless tangerines,” the sweet winter treats known as clementines are actually a variety of mandarin orange. Traditionally, clementines are said to be an accidental hybrid discovered by Father Clément Rodier in his garden in Algeria; they were introduced into California commercial agriculture in 1914. Although a clementine weighs only about half as much as a navel orange, ounce for ounce they are nutritionally similar: about the same amount of calories and potassium, while a navel orange contains slightly more fiber, vitamin C, calcium and folate per ounce. At only about 35 calories per fruit, clementines make an ideal snack.

You often report about research on “processed” meats. But what exactly does “processed” meat mean?

Answer :  According to the US Department of Agriculture (USDA), processed meat products may include, but are not limited to, bacon, deli/sandwich cuts, frankfurters, salami and sausage. Such products, derived from beef, pork, poultry or sheep, are processed and/or preserved beyond simply cutting, slicing, grinding, rolling or skewering. For example, processed meats may be canned, cured, brined or salted, pickled or smoked. Processed meats often contain nitrites, added as preservatives, stabilizers and coloring agents.

Is sauerkraut anticarcinogenic?

Answer :  

Cabbage, from which sauerkraut is made, is a cruciferous vegetable (like broccoli). The compounds that give cruciferous vegetables their sometimes-bitter taste and distinctive smell help protect the plants from insects and munching herbivores; when broken down in the human digestive system, these same compounds may help protect against cancer. Studies have shown that people who eat more cruciferous vegetables, including cabbage, were less likely to develop lung and bladder cancers.

Sauerkraut specifically contains isothiocyanates, compounds produced by fermentation of raw cabbage, which are being studied for anti-cancer properties. The Polish Women’s Health Study found that women who ate at least three servings a week of cabbage and sauerkraut were significantly less likely to develop breast cancer than those eating it only once a week.

I enjoyed your Special Report on “Food and Your Mood” (January 2010), but wanted to know more about serotonin. Is it true that eating foods high in tryptophan boosts serotonin levels? What about supplements sold as “mood enhancers” that are related to tryptophan?

Answer :  Tryptophan is an amino acid found in foods including poultry, peanuts and seeds, soy products, dairy, eggs and fish. It’s an essential amino acid, meaning your body can’t produce it; you must obtain it from your diet. Popularly, tryptophan is best known for its supposed power to put you to sleep after eating too much Thanksgiving turkey (in reality, all those carbs in the holiday feast are to blame). The body converts tryptophan into niacin and into serotonin, a neurotransmitter that regulates mood, anger and aggression, appetite and some cognitive functions. Antidepressants such as Prozac and Zoloft are selective serotonin reuptake inhibitors (SSRIs), which block the reabsorption of serotonin. When serotonin is converted to the hormone melatonin, it helps you sleep—hence the turkey tale.

When you eat foods containing tryptophan, the body converts some of it to kynurenine, which ultimately produces niacin. Other tryptophan gets converted into another intermediate compound, 5-hydroxy tryptophan (5-HTP).

Tryptophan supplements, once commonly used for insomnia, depression and anxiety, were banned in 1989 after toxic contaminants caused an outbreak of eosiniphilia-myalgia syndrome (ESS), characterized by muscle and joint pain, weakness, fever, swelling of limbs and shortness of breath. Recently, however, supplements of 5- HTP have appeared on the US market, promoted for positive mood and appetite control.

To learn more about tryptophan and 5-HTP, we consulted Erick H. Turner, MD, of the Portland VA Medical Center in Oregon, who authored a comprehensive review of the evidence on 5-HTP and serotonin. “I would argue that tryptophan is inefficient compared to 5- HTP,” Dr. Turner replied. “The idea is to get more serotonin synthesized in the brain. When you eat tryptophan, first of all, the lion’s share of it goes down the kynurenine pathway (to make niacin), and only a minority goes down the serotonin pathway. With 5-HTP, you’re already halfway down the serotonin pathway, so it can only go toward serotonin.

“However, you still have to worry about the 5-HTP being converted to serotonin before it gets into the brain, in which case you can get side effects related to serotonin’s action on various organs (e.g. nausea, flushing). This is not a disadvantage compared to tryptophan—what little tryptophan gets to the 5-HTP step will suffer the same fate. The way to minimize the amount of 5-HTP getting chewed up in the periphery— before it gets into the brain—is to give a peripheral decarboxylase inhibitor (PDI), such as carbidopa, which is available only by prescription.”

Nonetheless, Dr. Turner says it’s plausible 5- HTP supplementation could be effective in treating depression and anxiety, “since serotonin is implicated in anxiety disorders as well as depression (and many SSRIs are approved for both).”

Eating lots of turkey, however, is unlikely to significantly improve your mood.

Since calcium and vitamin D strengthen bones and vitamin A weakens bones, why is all reducedfat milk fortified with both vitamin A and vitamin D? And why is whole milk not?

Answer :  Robert M. Russell, MD, professor emeritus at Tufts’ Friedman School and former director of the Jean Mayer USDA Human Nutrition Research Center on Aging, explains: “It is true that in animals and man vitamin A in very high (toxic) doses can cause bone demineralization and a weakening of bones. Also, there have been some epidemiological studies that have shown a relationship between vitamin A intakes above one-and-a-half to two times the Recommended Dietary Allowance (RDA) and lower bone density, but this is far from proven. There are many other published studies that have not shown this relationship. At any rate, the vitamin A fortification level of skim and low-fat milk is low and safe (150 micrograms in a cup—whereas the RDA for an adult male is 900 micrograms per day). Low-fat and skim milk are required by the FDA to be fortified at this level, as the vitamin A is lost from the milk when the fat content is lowered (the baby is thrown out with the bathwater, so to speak). Whole milk still has plenty of fat and vitamin A content, which is absorbed well due to the fat that it travels with.”

I have read that pomegranate juice interferes with the availability and absorption of hypertension medication, in much the manner that grapefruit juice does. Is this true? If so, is the effect diminished by taking the juice hours before or after the medication?

Answer :  You can drink your pomegranate juice whenever you like, according to David J. Greenblatt, MD, professor and chair of the Department of Pharmacology and Experimental Therapeutics at Tufts’ School of Medicine. “Pomegranate juice does not have the same properties as grapefruit juice,” Dr. Greenblatt says. “Pomegranate juice has no effect on the absorption of any medications, and there is no concern with taking pomegranate juice with prescription drugs, regardless of the timing.”

I’ve often read in your newsletter that all fats contain about 120 calories per tablespoon. So why does my butter package say a tablespoon contains only 100 calories?

Answer :  The total calories per serving is different between oil and butter because a tablespoon of oil contain a full tablespoon of fat whereas a tablespoon of butter does not. According to Alice H. Lichtenstein, DSc, director of Tufts’ HNRCA Cardio - vascular Nutrition Laboratory, butter is about 20% water, by weight; it also contains some milk solids. Vegetable oil, however, is 100% fats, 0% water. A tablespoon of clarified butter (or “ghee”), which has been heated to evaporate the water and then skimmed to remove milk solids, does indeed contain about 120 calories. Although marginally lower in calories than a tablespoon of vegetable oil, that tablespoon of regular butter also contains 7.3 grams of saturated fat--a good reason to stick with liquid vegetable oils that are lower in this key culprit contributing to unhealthy cholesterol levels.

I have osteoporosis, and my doctor wants me to take 1,000 IU daily of vitamin D, along with my other daily vitamins, which also contain vitamin D. I calculate that this would bring my daily vitamin D total to 2,300 IU. Is this safe?

Answer :  It’s true that vitamin D can be toxic at extremely high levels and, technically, your total intake would be above the 2,000 IU daily Tolerable Upper Intake Level (UL) for vitamin D set by the Institute of Medicine. An expert panel is currently reviewing the recommended levels for vitamin D, however, and may recommend raising the UL as well as the Adequate Intake (AI); those recommendations are expected next year. Recent clinical trials suggest that the safe upper limit for vitamin D may be as high as 10,000 IU daily. Our advice in the meantime? Make sure your doctor knows about the other supplements you’re taking, and see if she thinks you should switch to a lower-dose vitamin D supplement. (For more on vitamin D, see our June 2009 Special Report.)

I’ve noticed that some cereals contain freezedried fruit. How does freeze-dried compare to fresh fruit in terms of nutrition?

Answer :  

The practice of freeze-drying foods dates to the ancient Incas, who would set out their crops on the slopes of the Andes, where the foods would freeze and then slowly dry in the low air pressure at high altitude. Modern freeze-drying, which employs a vacuum instead of thin mountain air, was first used for medical products such as blood plasma and for instant coffee. Nescafé, the first popular instant coffee, was introduced in 1938 by Nestlé to help Brazil use up a coffee surplus. Nestlé’s freeze-drying process sparked experiments with other foods, including fruit. Because freezedried foods are both long-lasting and lightweight, they proved ideal for feeding astronauts on space missions.

According to research presented at the 2006 American Institute for Cancer Research conference, freeze-dried fruits contain levels of antioxidants almost as high as the fresh originals. Freeze-drying does, however, seem to damage some fragile nutrients. Because freeze-dried fruits typically don’t contain added sugar, as many dried fruits do, they can be enjoyed “guilt-free,” much like fresh fruits.

The USDA Nutrition Database has not computed nutrient values for freeze-dried fruits, but it does contain data on freeze-dried sweet green (bell) peppers. A quarter-cup of freeze-dried peppers— which of course required considerably more volume of fresh peppers to make—has about the same amount of calories and vitamin C as a quarter- cup of fresh peppers; slightly less magnesium, phosphorus and potassium; roughly two-thirds the carbohydrates, total sugars, vitamin A and lutein; and about half the fiber and calcium.

Given the recent reports about bacterial contamination in nuts, does it make sense to heat nuts to a certain temperature before eating? This works for eggs and meat, why not nuts?

Answer :  

We checked your nut idea with Helen Rasmussen, PhD, MS, RD, an instructor at Tufts’ Friedman School and Senior Research Dietitian at the HNRCA Metabolic Research Unit. Happily, Rasmussen has a Tufts University School of Medicine student, Eva Litvak, working with her who could dig into this question in-depth.

Bacterial contamination of food can happen at any stage of food processing, from growth, to harvest, to storage, to packaging, to its final preparation. Any time foods are stored within a certain range of temperatures that are optimal for bacterial growth, the chances of contamination also increase. Eggs and raw animal products are much more likely to be exposed to bacteria during processing and must always be heated to appropriate temperatures during cooking. Though nuts may also be exposed to bacteria, most are dry-roasted after harvest, which kills bacteria at that stage of processing. Because of their high fat and low moisture content, however, heat-processing nuts may be a lengthy and unreliable method of preventing contamination at home.

For more information, see the National Institutes of Health website on “Bacteria and Foodborne Illness” digestive.niddk. nih.gov/ ddiseases/pubs/bacteria.

A friend in India claims that it is not advisable to eat fruit at the end of a meal, because the nutritional value of the fruit is diluted when it comes on top of other food. Is there any truth to this?

Answer :  

Tufts’ Rasmussen and Litvak again have the answer: After eating a meal, all the food we have consumed begins to break down in the stomach, where gastric secretions start to separate foods into the nutrients that our bodies can absorb. This food sits in our stomachs for minutes to hours as it is churned and emulsified. Then the stomach gradually empties its contents into our small intestine, where the absorption of nutrients begins. At that point, everything we have eaten during a meal has already been mixed together quite thoroughly. Whether you choose to eat fruit at the beginning or at the end of a meal will not diminish its nutritional value. The fruit is not adversely affected by any other foods it is eaten with. Our bodies are very good at taking all the nutrients we need from the foods we eat, regardless of the order in which we eat them.

After getting so many different answers, can you please tell me how bad is aspartame? I like chewing gum sweetened with it—two or three pieces a day— and people tell me I should cut down because aspartame is bad.

Answer :  

Keep chewing and stop worrying. The American Dietetic Association (ADA) recently completed a thorough review of the scientific evidence about aspartame and health (see NewsBites, August 2009). The findings debunked myths about aspartame, including the notion that it makes you hungrier (a so-called “rebound” effect) and that it somehow causes weight gain. The ADA also found no evidence for various Internet myths and “urban legends” about the sweetener, concluding: “Aspartame consumption is not associated with adverse effects in the general population.”

Those conclusions echo the position of the US Food and Drug Admini - stration (FDA), which states: “Since it was first approved for use in the United States, the safety of aspartame has been questioned by some. To date, however, the agency has not been presented with scientific information that would support a change in our conclusions about the safety of aspartame. Those conclusions are based on a detailed review of a large body of information, including more than 100 toxicological and clinical studies regarding the sweetener’s safety.”

Besides being kosher for religious purposes, what’s the difference between kosher salt and other salt?

Answer :  

AKosher salt, like most supermarket sea salt, is much coarser-grained than ordinary table salt. That makes it take up more volume for the same amount of weight, so you may need to adjust the amount used if a recipe calls for regular salt; check the koshersalt box for a conversion factor. (Morton, for example, says to use the same amount of kosher salt as specified for table salt, except in recipes requiring more than a quarter-cup; then you should add an extra tablespoon of kosher salt for every quarter-cup.)

Kosher salt does not dissolve as quickly as table salt, making it useful for giving a salty “feel” to the exterior of foods without using as much salt. In fact, this property is actually the reason for the name “kosher,” because kosher salt can be used to draw the blood out of meat, as prescribed by Jewish law. Almost all salt, including table salt, is kosher certified. Unlike most table salt, kosher salt is not iodized and is commonly free of other additives as well. (Morton kosher salt, however, contains yellow prussiate of soda—sodium ferrocyanide—as an anti-caking agent.)

As for sodium content, if you substitute kosher salt one-for-one for table salt, you will slightly decrease your sodium intake because of kosher salt’s greater volume: One teaspoon contains 1,920 milligrams of sodium, compared to 2,325 milligrams in table salt. By weight, however, both kosher and table salt contain about 400 milligrams of sodium per gram.

Is it contraindicated for individuals at risk of developing calcium oxalate kidney stones to take vitamin D3 supplements?

Answer :  Lesley Stevens, MD, MS, an assistant professor of medicine at Tufts, replies, “Vitamin D supplements are not necessarily contraindicated but would depend on why the person is at risk for the development of kidney stones. I suggest speaking to their doctor first.” That’s good advice for most supplements if you’re at risk for kidney stones, according to the National Kidney Foundation, which suggests, “Check with your doctor or dietitian for advice on the use of vitamin C, vitamin D, fish liver oils or mineral supplements containing calcium since some supplements can increase the chances of stone formation in some people.”

In your May issue you illustrated the “radura” sign for food treated by irradiation. A caterer told me all pork is irradiated to prevent trichinosis; that is why it can be served when the meat is still pink inside. However, pork sold in grocery stores does not have this sign on it. Is it true that pork is safe to eat when cooked this way? I was taught to cook pork until it was gray inside.

Answer :  

You might want to switch caterers. Trichinosis is caused by ingestion of the Trichinella spiralis parasite, also known as trichina. According to the US Department of Agriculture (USDA), “Irradiation has been approved for use on pork by FDA and USDA/ FSIS in low-doses (to control trichina). Treated pork would not be sterile and would still need to be handled safely. Trichinella could be alive but would be unable to reproduce. Packages of irradiated pork must be labeled with the irradiation logo as well as the words ‘Treated with Irradiation’ or ‘Treated by Irradiation’ so they would be easily recognizable at the store.” So it’s not true that all pork has been irradiated, and pork that has been irradiated must bear the “radura” sign plus this labeling.

That doesn’t mean, however, you need to cook pork until it’s gray inside. Meat color, in fact, is not a reliable indicator of temperature and food safety; it’s better to invest in a good meat thermometer. Although the Centers for Disease Control and Prevention (CDC) continues to recommend cooking to 170 degrees to prevent trichinosis, the USDA states, “Much progress has been made in reducing trichinosis in grain-fed hogs, and human cases have greatly declined since 1950. Today’s pork can be enjoyed when cooked to an internal temperature of 160 degrees.” That temperature—at which pork might still appear slightly pinkish—is also hot enough to kill foodborne bacteria such as E. coli and salmonella. To learn more about pork preparation and safety, see www.fsis.usda.gov/Factsheets/Pork_From_Farm_to_Table/index.asp.

I have long read recommendations of low-fat milk. How about powdered milk? I have used it for about 50 years—mixed extra rich—for the vitamin D, calcium and no fat.

Answer :  Just like regular milk, powdered or “dry” milk comes in different types. The most important difference is whether the milk is nonfat or whole. If you’re reconstituting whole powdered milk, you’re getting 159 calories and 5.3 grams of saturated fat from every quarter-cup of powder. But if you stick to nonfat dry milk, a quarter-cup of powder contains just 109 calories and only trace amounts of fat, while still containing 100 IU of vitamin D and 377 milligrams of calcium—amounts similar to ordinary skim milk. Mixing dry milk “extra rich” would indeed boost the nutrients (as well as the calories)—just make sure you’re buying the nonfat variety, or it would truly be “extra rich” in fat and calories.

I take a multivitamin with my morning cup of tea. Do I need to be worried that the tea might block the absorption of the vitamins?

Answer :  

In general, there’s no need to be concerned about tea blocking the absorption of vitamins or other nutrients, according to Jeffrey B. Blumberg, PhD, director of the Antioxidants Research Laboratory at Tufts’ Jean Mayer USDA Human Nutrition Research Center on Aging, who has studied tea at length. “The extensive history of daily, long-term intake of tea indicates a high level of safety, although that usage does not adequately address the issue scientifically,” Blumberg says. “Other than the issue of caffeine intake, I am aware of only two documented situations where tea may have an adverse impact on nutritional status.” These involve the possibility that tea might affect levels of folate and iron in the body.

In the first case, while many observational studies and some clinical trials suggest tea reduces the risk of cancer, a few test-tube studies suggest a potential pro-carcinogenic mechanism of tea catechins (naturally occurring antioxidant compounds) by reducing folate levels. In the only human study available to date examining this effect, researchers tested a green-tea extract and a black-tea extract in a crossover randomized clinical trial. The study measured bioavailability—the ability of the body to use a nutrient—by giving a high dose of folic acid to seven healthy individuals and then measuring their blood levels of folate. Only the green-tea extract, which contained 51 milligrams of green-tea catechins, significantly reduced folate levels.

In the second instance, a systematic review addressed concerns about the potential of tea to inhibit the absorption of iron—specifically the “nonheme” iron found in plants as well as in animal tissue. The 35 studies on iron absorption and black tea that were reviewed didn’t include any clinical trials. Based on the 12 highestquality studies, there was a measurable inhibition of iron bioavailability, but one that presents no threat to healthy adults with normal iron status. “While this may present the potential for an adverse impact in people with iron-deficiency anemia,” Blumberg notes, “it may also present a benefit to people (especially older men) with a high iron intake, as some studies suggest increased iron status is a risk factor for cardiovascular disease.”

I take supplements of vitamin B12 daily, plus a “mature” multivitamin containing vitaminB12. Should I be worried about the risk of overdosing on vitamin B12?

Answer :  Unlike many other nutrients, the Institute of Medicine has not established a Tolerable Upper Intake Level for vitamin B12, so there’s no official point at which taking B12 becomes “too much of a good thing.” According to Jacob Selhub, PhD, director of the Vitamin Metabolism Laboratory at Tufts’ Jean Mayer USDA Human Nutrition Research Center on Aging, however, the body’s absorption of vitamin B12 is very limited, irrespective of dose. So there’s no need to worry about overdosing on B12 in supplements or in food.

We’ve read that drinking a lot of fruit juice or eating a lot of turmeric or blueberries can help prevent Alzheimer’s. But isn’t it futile after 50 or 60 years to try this? Wouldn’t it take a lifetime of eating these foods to do any good? At what age approximately does it really not make any difference?

Answer :  James Joseph, PhD, research physiologist at the Neuroscience Laboratory at Tufts’ Jean Mayer USDA Human Nutrition Research Center on Aging, answers: “We now have data from one of our collaborators which shows that aged individuals (average age in their 60s) exhibiting early memory declines who were given Concord grape or blueberry juice (approximately 12 ounces per day) showed improvements in memory on several parameters, such as list recall, intrusion errors, etc. In addition, all of our initial studies with blueberries, strawberries, blackberries or walnuts were done in old animals. So it is never too late to start.”

Your March 2009 newsletter discusses obesity, as measured by Body Mass Index (BMI). Would you please advise how to calculate BMI?

Answer :  

The easiest way to calculate BMI, especially for the math-phobic, is to enter your height and weight into one of the many BMI calculators on the Web, such as the National Heart, Lung and Blood Institute’s page at www.nhlbisupport.com/bmi. If you’d rather do it youself, the standard formula requires you to convert your weight from pounds into kilograms (divide by 2.2) and height from inches into meters (divide by 39.37). To figure BMI, divide your weight in kilograms by your height in meters squared. If you’d rather skip the metric system, try this: weight in pounds x 703 / height in inches 2. Either way, for example, a person who’s 165 pounds and 5-foot-9 (69 inches) has a BMI of 24.4.

I’ve heard that California almonds are being irradiated. Does this mean that these almonds no longer have any nutritional value? Are they harmful to eat?

Answer :  

A Irradiation is one of the possible methods to satisfy a 2007 USDA requirement that raw almonds be pasteurized to prevent foodborne illness, such as the salmonella outbreaks in 2001 and 2004 traced to raw almonds. According to the Almond Board of California, however, “Radiation as a pasteurization method has been considered, but not actively pursued.” And a spokesperson for the almond trade group confirms that no California almonds are being irradiated.

You may encounter other foods, however, that have been irradiated to kill foodborne bacteria. Last year, for example, in the wake of illnesses traced to contaminated leafy vegetables, the US Food and Drug Administration (FDA) approved a rule modification to permit the (optional) irradiation of fresh iceberg lettuce and fresh spinach at the maximum absorbed dose. The FDA has determined that the process is safe and effective in decreasing or eliminating harmful bacteria on a variety of foods. Irradiation of foods is allowed in nearly 40 countries and has been endorsed by the World Health Organization and the American Medical Association. Foods that have been irradiated do not lose any of their nutritional value.

Nonetheless, irradiated foods remain controversial and some consumer groups have expressed concerns about their safety. If you prefer to avoid irradiated foods, simply check the package label: All foods that have been irradiated must carry the international symbol for irradiation, the “radura” (shown here), as well as the phrase, “treated by irradiation” (or “with irradiation”). You can also opt for organic foods, since irradiation is not acceptable under the rules of the USDA National Organic Program; thus, foods labeled “organic” cannot be irradiated.

QI’ve read that wild blueberries are good for you, but most of us have access only to cultivated berries. Does this mean that cultivated berries are not as good for you?

Answer :  

AIt’s true that USDA testing in 2004 found that wild blueberries had more antioxidant capacity than the same size serving of cultivated blueberries (while also scoring higher than cranberries, strawberries, plums and raspberries). But the nation’s leading researcher on the health benefits of blueberries, James A. Joseph, PhD, a research physiologist at Tufts’ Jean Mayer USDA Human Nutrition Research Center on Aging, says that from a nutritional standpoint, wild and cultivated blueberries can be considered equal.

Tufts researchers and others are studying blueberries’ antioxidant benefits, including the promise that they could boost brain functions that weaken with aging. Other research has suggested that blueberries may help improve cholesterol levels, protect against stroke, aid urinary- tract health and even inhibit tumor growth.

If you really want to seek out wild blueberries, note that they can often be found frozen. Whether wild or cultivated, frozen blueberries are an economical way to “go blue” even when fresh berries are out of season; typically frozen when the berries are at their peak, they offer the same nutritional benefits as fresh.

QI like fresh salmon, but it’s too expensive so I buy canned salmon. Is canned salmon as nutritious as fresh?

Answer :  

AComparing canned salmon (liquids drained) with an equal quantity of cooked fresh salmon, each offers some nutritional advantages. The differences derive from how canned fish is processed, and from the fact that bones are included in canned salmon. Those edible bits of bone give canned salmon significantly higher levels of calcium (18 times as much) and phosphorus per serving than fresh salmon. Canned salmon also has more vitamin D. On the downside, canned salmon contains more than six times as much sodium—399 milligrams per 100 grams (about 3.5 ounces)— as fresh salmon. Both canned and fresh salmon give you roughly the same amount of protein, 22-23 grams per 100 grams.

Some of the fat found in fresh salmon is lost in processing, meaning canned salmon has only two-thirds the calories of the same amount of the cooked fresh fish. Unfor - tunately, some of the heart-healthy omega-3 fatty acids that salmon is prized for get lost as well; canned salmon has only about half the total amount of the two most important omega-3s, EPA and DHA, found in a comparable serving of fresh salmon.

So canned salmon can be part of a healthy diet, though you’ll need to eat it more frequently to get enough omega-3s.

QI am confused by whether shrimp and other shellfish are good in the diet due to attributes such as being high in protein, low in fat and low in calories, or bad because they are high in cholesterol. Please clarify.

Answer :  

AThe good news for shrimp and other shellfish is that the major dietary factor that raises LDL (“bad”) cholesterol is saturated fat, not dietary cholesterol, according to Alice H. Lichtenstein, DSc, director of the Cardiovascular Nutrition Laboratory at Tufts’ Jean Mayer USDA Human Nutrition Research Center on Aging. Although a three-ounce serving of shrimp has 166 milligrams of cholesterol— more than half what you should consume in a day—it has almost zero saturated fat. So shrimp and other shellfish are a good substitute for entrees containing meat and dairy fat, both high in saturated fat. At just 84 calories in a three-ounce serving of shrimp, it can also help keep down your diet’s calorie count—as long as you don’t batter and fry the shrimp or serve swimming in butter!

Shrimp are also a source of protein (18 grams per serving), vitamin B12, selenium, niacin, iron, phosphorus and zinc. Be aware, however, that you can’t count on shrimp and other shellfish for the health-promoting omega- 3 fatty acids found in salmon and other fatty fish. A serving of shrimp contains only 295 milligrams of total omega-3s—about one-sixth the amount in a comparable serving of salmon.

QBack in the 1950s, Carlton Fredericks, a popular radio personality, touted the virtues of blackstrap molasses. Mom bought some for Dad, but after one taste it was history. About a year ago, though, I ran across it in the store and was amazed that it appears to be a “superfood.” Why have you never mentioned blackstrap molasses in your newsletter?

Answer :  

AMolasses is a concentrated byproduct of refining sugar cane into table sugar. ”Black strap” molasses comes from the third and final boiling of the sugar syrup, so this strongly flavored, thick, dark molasses variety is highest in mineral content and lowest in sugar. Unlike sugar or artificial sweeteners, molasses is a source of minerals your body needs, including manganese, magnesium, iron, copper, calcium and potassium. Amounts vary widely by brand, so check the label if you’re buying molasses for its mineral content. And before you start gulping blackstrap molasses as a “superfood,” keep in mind that each tablespoonful also has about 50 calories.

I know that 100% whole-wheat bread is better for you than white bread. But how nutritious are breads such as rye and pumpernickel?

Answer :  

Both rye bread and pumpernickel bread are typically made with a mix of rye flour and wheat flour. Brands vary widely as a source of whole grains, so check the ingredients list on the label for “whole rye flour” and “whole wheat flour.” Besides being a whole grain—just like whole wheat—rye is a good choice for people watching their glycemic index (a measure of how rapidly the body converts food to sugars), such as diabetics. Rye has an unusually high level of fiber in its endosperm, the inner part that serves as a seedling’s food supply. (When grains are processed rather than whole, the outer bran and germ are stripped away and the endosperm is all that remains.) This fiber-rich endosperm generally gives rye products—including rye bread and pumpernickel bread—a lower glycemic index than products made from wheat. On most other measures of nutritional value, rye and pumpernickel bread are not significantly different from regular whole-wheat bread. Both are richer sources of folate and folic acid and, depending on the brand, may be marginally lower in saturated fat. Whole-wheat bread is higher in protein and magnesium while typically lower in sodium per slice. All three types of bread contain about the same amount of calories per serving.

I enjoy eating buffalo meat when I am able to buy it from local farmers. It’s very lean, but is it more healthful than regular beef in other ways?

Answer :  

Buffalo (bison) meat is indeed much naturally lower in fat than beef from cattle. Its proportion of saturated, polyunsaturated and monounsaturated fat is very similar to that of beef, so the fact that bison has only one-quarter to one-fifth the overall fat means you’re getting that much less saturated fat per serving. Since fat is a dense source of calories, bison meat generally has only about two-thirds the calories of the same quantity of beef. Bison is also slightly lower per serving in dietary cholesterol than beef and higher in iron and vitamin B12.

Because of its lower fat content, bison shrinks less and cooks a little faster than beef. That can also make it tough when cooked beyond medium or when cooked at high temperatures; some buffalo-meat purveyors recommend slow roasting at no more than 275 degrees. Such low temperatures can be a food-safety issue, so be sure to freeze raw buffalo meat or keep it refrigerated at 40 degrees.

Do egg yolks really differ from egg whites in terms of raising “bad” (LDL) cholesterol? What’s a safe weekly limit for both parts of the egg?

Answer :  

A Yolks contain the fat and cholesterol in an egg, in addition to protein, vitamins and minerals. The whites contain primarily protein, only a very little fat and no cholesterol. Eggs have gotten a bad rap as a cholesterol culprit, because they are a concentrated source of cholesterol in the diet and there’s confusion between dietary cholesterol and blood cholesterol. While dietary cholesterol can contribute to unhealthy LDL levels in some, the primary dietary cause of LDL problems is saturated fat.How many eggs can you safely eat? Egg proponents cite a 1999 study of 117,000 adults that found little impact on the risk of heart disease or stroke from consuming one egg a day. Current recommendations, however, are that individuals with healthy LDL cholesterol concentrations eat 300 milligrams of dietary cholesterol or less per day. With 210 milligrams of dietary cholesterol in the yolk of one large egg, a single egg at breakfast puts you at about two-thirds of your daily maximum. If you are limiting saturated fat in your diet, by minimizing animal fat intake (meat and dairy), staying within the limit should not be a problem. If you are more liberal with your intake of animal fats, it may be wise to be a little more careful about egg intake.

Fortunately, for people who want or need to limit their dietary cholesterol and want their daily eggs as well, there are a couple of good options: Make an omelet with 1 whole egg and two egg whites or use egg substitutes.

It is currently recommended that individuals with high LDL cholesterol concentrations should try to limit their intake to 200 milligrams of cholesterol or less per day. For some of these individuals, sometimes referred to as “cholesterol responsive,” dietary cholesterol such as that in eggs can have a big effect on their LDL cholesterol concentrations.

I know it can be harmful to eat charred, blackened meat. Is the same true of overtoasted nuts, burnt potatoes and the like?

Answer :  A We posed this question to Rashmi Sinha, PhD, senior investigator at the National Cancer Institute and a leading expert on carcinogens in charred foods. His answer might be characterized as good news, bad news: Unlike blackened meat, charred vegetables do not have one group of carcinogenic compounds, heterocyclic aromatic amines. But they probably do contain polycyclic aromatic hydrocarbon compounds that have also been linked with cancers in animals. So to be on the safe side, trim any burnt edges and discard badly charred vegetables.

How does microwaving affect the nutritional value of food?

Answer :  

We posed this question to Helen Rasmussen, PhD, RD, senior research dietitian at Tufts’ Jean Mayer USDA Human Nutrition Research Center on Aging. It turns out that the effect of microwave cooking on the nutritional value of food is an intriguing question—so much so that Rasmussen put one of her students on the case, Emily Evans, a master of science candidate at Tufts’ Friedman School. Microwaving is usually faster than other cooking methods, Evans points out, and may actually have some advantages when it comes to preserving nutrients. For one thing, microwaving uses less water than boiling, and foods cooked in water lose more nutrients than those cooked without. Microwave ovens also typically use less heat than other cooking methods, making them less destructive. Water-soluble vitamins such as vitamins B, C and folic acid are very heatsensitive. Recent studies at Cornell University found that spinach cooked in the microwave kept most of its folic acid, but lost about 77% when cooked on the stove.

The bottom line, according to Evans:Microwave cooking does not cause significant loss of human health-related nutrients in foods, as long as the amount of water used and cooking time are limited.

I take flax-oil supplements every day and I was alarmed to read in your September 2008 issue that high intake of alpha-linolenic acid (ALA), found in flax, was actually associated with an increase in risk for early age-related macular degeneration (AMD). Should I stop taking flax oil?

Answer :  We checked with the lead researcher on that study, Elaine W. T. Chong, MBBS, of the University of Melbourne in Australia, who replied: “This does not mean that our results are definitive. People should not be overly concerned regarding ALA flax-seed capsule intake. However, they should be aware that it is the long-chain omega-3 fatty acids (DHA and EPA) that have been associated with a protective effect for AMD and other health conditions,and less so ALA.”

Is buckwheat a grain or is it actually a seed? I have it for breakfast every morning, and am wondering if I’m getting all the benefits one gets from grains.

Answer :  According to the Whole Grains Council www.wholegrainscouncil.org, buckwheat is neither a grain nor, despite its name, a relative of wheat; botanically, it’s a cousin of rhubarb. But nutritionally, buckwheat qualifies as a “whole grain,” so your morning routine is fine. The part of the buckwheat plant that we eat, ground into flour or hulled for groats (called “kasha” in the US), is indeed the seed. A half-cup of dry buckwheat groats contains 8.4 grams of dietary fiber—more than twice a comparable serving of oatmeal. Buckwheat is also the only “whole grain” known to have high levels of an antioxidant called rutin that improves blood circulation and may keep LDL cholesterol from blocking blood vessels. People with celiac disease or gluten allergies can safely consume buckwheat, because it contains no gluten.

How can I keep from overeating during the holidays?

Answer :  Helen Rasmussen, PhD, RD, an instructor at Tufts’ Friedman School, enlisted Laura Ficker, a master’s candidate at the school, to offer these holiday tips:
• Don’t go to holiday parties and dinners hungry. It’s easy to eat faster and greater amounts when you’re hungry. Eat a wholesome breakfast and lunch to avoid overeating later in the day.
• Be conscious of the food around you. Fill your plate one time, half with vegetables, one quarter with a lean meat and the rest with starches of your choice. Eat slowly and stop when you are full.
• Make a conscious choice to limit high-fat items. High-fat ingredients can be found in fried, creamy and cheese-filled dishes associated with the holidays. If you can’t control the ingredients that go in to a dish, simply limit yourself to a smaller helping size.
• Drink plenty of water. Alcohol and coffee in excess can dehydrate your body. Additionally, eggnog and other holiday drinks can easily add 350-400 calories per drink. Choose calorie-free water to help fill up your stomach and keep you hydrated.
• If you’re the cook, decrease the fat in your gravy. Use a fat separator or refrigerate the pan juices and skim the fat off before making the gravy. This can save up to 55 grams of fat per cup (495 calories) and help you avoid having greasy gravy.
• Avoid leftovers. Give them away or choose not to take any home. Not having heaps of leftovers looming makes it easier to get back into a normal and healthful food routine when the holidays are over.

Your newsletter often states the advantages of omega-3 fatty acids. But how much fish should I consume to benefit?

Answer :  Both the American Heart Association and the 2005 federal Dietary Guidelines for Americans recommend consuming at least two servings of fish per week for heart health. The dietary guidelines, whose fish recommendation specifically targets people who have already experienced a cardiac event, go on to spell out that two servings should total approximately eight ounces. Not just any fish will do for omega-3s, however: “It’s best to go with ‘dark’-fleshed fish, such as salmon, trout or tuna,” advises Alice H. Lichtenstein, DSc, director of the Cardiovascular Nutrition Laboratory at Tufts’ Jean Mayer USDA Human Nutrition Research Center on Aging. “Fried fish fillets don’t count, due to the low omega-3 levels in the type of fish usually used, added calories that come from the cooking process and the potential for trans fats from the type of fat used to fry the fish in.”

With the increasing evidence for the benefits of vitamin D, is there any artificial light that will give me the benefits of sunshine in making vitamin D?

Answer :  

While not even the most avid vitamin D advocate suggests broiling yourself in a tanning booth, it is true that people in northern climes can’t get enough sunshine during winter to trigger the body’s natural ability to make vitamin D. The easiest alternative is to take vitamin D supplements. But if you prefer to bring the sun indoors, you’ll need a special kind of “medium-pressure” lamp that puts out the UVB rays the body uses in making vitamin D.Many so-called “sunlamps” (such as those designed to combat Seasonal Affective Disorder) and tanning salons use only “high-pressure” lamps that produce UVA light but not UVB—increasing your risk for skin cancer without producing vitamin D. The US Food and Drug Administration has sanctioned some sunlamps made by Sperti (, 859-331-0800), such as the KDB D/UV lamp, as a vitamin-D producer for people who have trouble absorbing vitamin D from food, such as those with gastric bypass surgery, Crohn’s disease or cystic fibrosis.

There is no official recommendation for UVB exposure, from the sun or sunlamps, although a review article last year in the New England Journal of Medicineconcluded, “Exposure of arms and legs for 5 to 30 minutes (depending on time of day, season, latitude and skin pigmentation) between the hours of 10 a.m. and 3 p.m. twice a week is often adequate.” The nonprofit Vitamin D Council says 15 to 20 minutes of noonday sun exposure (or when “the sun is high enough in the sky so that your shadow is shorter than you are”), twice a week, will give most fair-skinned people in most of the continental US enough of the vitamin. If using a sunlamp, 10 to 15 minutes twice a week is probably plenty, and you should apply sunscreen to protect your face, since facial skin makes very little vitamin D.

My doctor has prescribed me Coumadin (warfarin) to fight blood clots. I see that you’re supposed to avoid foods that contain “large amounts” of vitamin K when taking warfarin. Can you offer any more specific guidance as to what “large amounts” means?

Answer :  

We checked with Sarah L. Booth, PhD, director of the Vitamin K Laboratory at Tufts’ Jean Mayer USDA Human Nutrition Research Center on Aging, who shared the advice on warfarin and vitamin K she’d recently reviewed for the Tufts-New England Medical Center: Vitamin K helps blood to clot, so it can change the way warfarin works. This does not mean you need to stop eating foods high in vitamin K, such as leafy green vegetables, which are also high in other heart-healthy nutrients. Your goal is to keep your diet consistent by eating the same amount of vitamin K foods from week to week. This will help warfarin to work its best. If you are not able to eat for a few days, or you are going to make big changes to your diet, call your doctor.

The rule of thumb is the greener the plant, the more vitamin K. You should aim to eat a similar mix of foods very high, high and medium in vitamin K daily. Foods very high in vitamin K (serving size 1/2 cup) include spinach, escarole, kale, seaweed, endive and collard greens. Turnip greens and Swiss chard are high in vitamin K. Medium foods include broccoli, Brussels sprouts, Romaine lettuce (1 cup), parsley (10 sprigs), green cabbage, spring onions, cole slaw, pistachios and mustard greens. Other vegetables and all fruits are low sources of vitamin K. Multivitamins and liquid nutrition supplements such as Ensure and Boost also contain vitamin K, so keep your use of these the same from week to week.

Also keep in mind that cranberry and grapefruit juice can increase warfarin in your blood; limit to four ounces per day. Vitamin E, fish oil supplements and alcohol in high amounts can change the way warfarin works. Herbal supplements should not be taken with warfarin. If in doubt, talk to your doctor.

Dr. Dean Ornish claims that olive oil reduces blood flow by 31%. Is this true and if so is it a reason to stop using olive oil?

Answer :  Ernst J. Schaefer, MD, director of the HNRCA Lipid Metabolism Laboratory at Tufts, explains that the problem with olive oil—despite all of the hype about its benefits—is that it is low in essential fatty acids (either omega-6 or omega-3). Olive oil contains about 85% monounsaturated fatty acids, mainly oleic acid, and about 15% saturated fatty acids, mainly palmitic acid. In contrast, soybean oil has only about 8% saturated fat, and has a lot more essential fatty acids—both omega-6 (mainly linoleic acid) and omega-3 (mainly alpha-linolenic acid, ALA). Canola oil also has quite a bit of ALA—an omega-3 fatty acid—and much more omega-6 than olive oil, though somewhat less than soybean oil. Fish oil, of course, contains at least 50% eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)—the omega-3 fatty acids that are good for the brain and the heart in terms of preventing arrhythmias and dementia.

When Dr. Ornish cites a study that olive oil reduces blood flow by 31%, he is talking about brachial artery (the main artery of the upper arm) reactivity and not coronary blood flow. It is true, however, that monounsaturated oils such as olive oil may not be the best choice to protect against the accumulation of fatty deposits in the inner linings of the arteries. Tufts’ Dr. Schaefer notes that Laurence Rudel, PhD, of Wake Forest University has done careful monkey studies indicating that polyunsaturated fatty acids are more beneficial than saturated fat or monounsaturated fat in preventing diet-induced atherosclerosis. Therefore, while olive oil need not be avoided, other vegetable oils such as canola, soybean and other oils high in polyunsaturated fat are better options for essential fatty acid consumption.

Is frozen yogurt as nutritious as regular yogurt? What happens to live cultures such as acidophilus when yogurt is frozen?

Answer :  Simin Nikbin Meydani, DVM, PhD, professor of nutrition at the Friedman School and associate director of Tufts’ Jean Mayer USDA Human Nutrition Research Center on Aging, responds:

“The nutritive value of yogurt or frozen yogurt is based on the ingredients in the yogurt, so it will be slightly different for frozen yogurt made by different companies. The labels should provide the nutritional information. [Since frozen yogurt is a dessert, it’s typically sweetened; make sure to also check the label to see how much added sugar you’re getting.]

“Yogurts and frozen yogurts can contain live active cultures. Manufacturers might add extra ‘healthy’ bacteria (such as L. acidopihilus, Bifidobacteriumor and others) for their health effects, but not all yogurts have these extra probiotic bacteria. Although the flash-freezing technique used in the production of frozen yogurt, unlike slow freezing in a freezer, should not kill the live cultures, there is no guarantee that this won’t occur.

“As a result, the number of bacteria in frozen yogurt is usually lower than that in the yogurt it was made from. Different yogurts and frozen yogurts are made with different types of live cultures and probiotics, however, and the levels that remain in frozen yogurt depend on the numbers that were in the yogurt and on the heartiness of the specific bacteria that was used.

“The National Yogurt Association sponsors a voluntary labeling program for frozen yogurt; look for the ‘Live and Active Cultures’ seal on containers of frozen yogurt. If the yogurt doesn’t have the label, contact the manufacturer and ask what types of bacteria their product contains and at what level.

“Some frozen yogurts may be better sources of probiotics than some regular yogurts. The National Yogurt Association standard for a live active culture frozen yogurt is 10 million cultures per gram at time of manufacture; for yogurt it is 100 million.”

What can you tell me about the possible toxic effect of peanut oil lectin (PNA)? I’ve read where the “Paleo Diet” cites research showing that PNA from peanuts and peanut oil clogs the arteries.

Answer :  We tracked down one of the original researchers in those 1998 studies, David Klurfeld, PhD, who is now a national program leader in human nutrition with the USDA’s Agricultural Research Service. He replies:

“A little background is in order to understand why we did those studies many years ago. Rabbits and monkeys fed peanut oil had more cardiovascular lesions than expected from a polyunsaturated oil—almost as much as from the most saturated fats. I developed a method that extracted lectin from vegetable oils and we found lectin in all refined oils at extremely low levels. Peanut lectin is a protein that binds to a carbohydrate on endothelial cells, which line blood vessels. And this lectin differs from lectins found in other seed oils. So it was plausible that lectin explained some or all of the unexpected effects on lesion formation.

“Since then, epidemiological and, more important, intervention studies with peanuts and many types of tree nuts have shown not only no increase in serum cholesterol or risk of heart disease but a reduced risk. So there is, in my opinion, no harm from consumption of peanuts or peanut oil. This story has developed a life of its own and has been perpetuated on the Internet along with similar fables.”

When nutritionists talk about walnuts, do they mean black or English walnuts?

Answer :  According to the California Walnut Board, a trade association, the walnuts you buy in stores—and those most commonly touted for nutritional benefits—are “English walnuts.” The “black walnut” is a native American species that’s primarily used as a rootstock for English walnuts. If you have black walnuts growing in your yard, you’ll find the meats are tasty, but a lot of work to crack and remove from the shell. Nutritionally speaking, black walnuts contain 10% less total fat and 20% less omega-3 fatty acids than English walnuts. One ounce of black walnuts—about 14 halves—has 175 calories, 16.7 grams of total fat and 0.57 grams of omega-3s. One ounce of English walnuts has 185 calories, 18.5 grams of total fat and 2.6 grams of omega-3s. Note that the highly promoted omega-3s in walnuts are in the form of alpha linolenic acid (ALA), which the body must convert to the healthful omega-3s found naturally in fish—an inefficient process.

We live in southern Arizona where citrus trees thrive and own two well-producing grapefruit trees. Are there prescription drugs that do not act well with grapefruit?

Answer :  According to the Center for Food-Drug Interaction Research and Education, led by Tufts and the University of Florida, most prescription drugs do not show a clinically relevant interaction with grapefruit juice—despite popular belief. In the late 1980s, scientists discovered that grapefruit juice contains natural substances that can affect the way certain prescription medications are broken down (metabolized) by an enzyme, known as CYP3A4. If a person drinks grapefruit juice and takes one of these drugs orally, more of the drug may enter the bloodstream than would have under normal circumstances. This means that grapefruit juice has the potential to enhance the absorption of these drugs. The extent of a potential interaction will vary from drug to drug, and even from person to person. For a guide to degree of interaction with medications by brand name, see the center’s Web site at grove.ufl.edu/~ned/fdic/consu.php?interaction_category=9. Patients should consult with their pharmacist or doctor if they have any questions about their prescription medication(s). For patients taking medications known to interact with grapefruit juice, there generally are non-interacting, alternative medications that offer safe treatment with no need to discontinue drinking grapefruit juice. All studies reviewed by the center support that it is safe to consume grapefruit juice while taking over-the-counter medication.

My eczema has become worse over the last few years. Are there any foods that I should avoid?

Answer :  Eczema is a chronic skin disorder due to a hypersensitivity reaction—similar to an allergy—in the skin. The role of diet is difficult to pinpoint and may vary by individual, much as with food allergies; most research on food and eczema has focused on children rather than adults. According to the National Institutes of Health (NIH), possible dietary restrictions for eczema sufferers may include eggs, fish, peanuts and soy.

How does tapioca rate nutritionally? Does it fall under the refined food category? I like to use it to make tapioca pudding with Splenda and nonfat Lactaid milk and eat about one cup of the pudding as a dessert twice a day. Should I cut back?

Answer :  People have been eating tapioca at least since the heyday of the Mayans, who first figured out how to process the root of the cassava plant (also called manioc or yuca) to eliminate its naturally occurring cyanide. Technically, yes, tapioca is a refined food in the sense that the packaged tapioca you buy is made from reconstituted, processed root; being a root starch, rather than a grain, however, there’s no such thing as “whole” tapioca. Nutritionally, tapioca is pretty much as neutral as it tastes: The dry mix used to make one cup of tapioca pudding (not counting milk or any sweetener) contains 170 calories, 43 grams of carbohydrates, 219 milligrams of sodium, and only tiny amounts of protein, fiber, vitamins and minerals. So, if tapioca pudding satisfies your craving for dessert, you’re probably not doing yourself any harm, but you’re not gaining much nutritionally, either. By comparison, while not ordinarily considered “dessert,” a bowl of oatmeal offers much the same consistency plus a whole-grain nutritional bonanza: One packet of instant oatmeal also has 170 calories, but adds 4 grams of protein, 3 grams of fiber, and a healthful mix of minerals and vitamins. So you might try opting for oatmeal at least once a day instead of tapioca.

I read a report recently indicating that all nuts contain monosaturated fat. I thought this was true only of almonds, and that the rest contain polyunsaturated fat. Am I wrong?

Answer :  All popular nuts contain both types of fat— and the good news is that both mono- and polyunsaturated fat are “heart-healthy” compared to saturated and trans fats. According to the American Heart Asso ciation, “Monounsaturated fats and polyunsaturated fats appear to not raise LDL cholesterol; some studies suggest they might even help lower LDL cholesterol slightly when eaten as part of a low-saturated and trans-fat diet.” Each type of nut does differ in its proportion of mono- and polyunsaturated fats, with macadamias actually the highest in monounsaturated fat. Walnuts are also high in a special kind of polyunsaturated fatty acid, alpha linoleic acid (ALA), which the body can convert to the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), known for a wealth of health benefits; this is not a very efficient conversion, however, so your best source of omega-3s is still fatty fish like salmon, not nuts. The chart above shows how the fat content (in grams) of one ounce of whole nuts compares by type of nut or legume.

Keep in mind that nuts are only one way to incorporate monounsaturated fats and polyunsaturated fats into your diet. Other ways include using vegetable oils such as soybean and canola in salad dressings and while cooking. Remember that even “heart-healthy fats” contain calories, so although they may be good for you, that’s only when they replace something less-healthy in your diet. Also watch out for added salt in the nuts you’re munching-- and be aware of the total amount you consume.

Monounsaturated Polyunsaturated ALA
Almonds 8.8 g 3.4 g less than 0.1 g
Cashews 6.7 g 2.2 g less than 0.1 g
Macadamias 16.7 g 0.4 g less than 0.1 g
Peanuts 6.9 g 4.4 g less than 0.1 g
Pecans 11.6 g 6.1 g 0.3 g
Pistachios 6.6 g 3.8 g less than 0.1 g
Walnuts 2.5 g 3.4 g 2.6 g

Is much of the omega-3 lost when the skin of the salmon is discarded?

Answer :  According to Alice H. Lichtenstein, DSc, director of the Cardiovascular Nutrition Laboratory at Tufts’ Jean Mayer USDA Human Nutrition Research Center on Aging, much of salmon’s healthy omega-3 fatty acids lie just under the skin. Comparing total omega-3s for the same variety of salmon in different preparations using the USDA’s Nutrient Database, salmon without the skin contains only 39% to 64% of the omega-3s in the same portion of salmon with the skin. But there’s a downside to leaving the skin on salmon, Lich - tenstein cautions: That same fatty layer next to the skin may also contain some fat-soluble contaminants, if present. If you’d rather not eat the skin, you can make up for any omega-3s that get lost to the trash by buying varieties of fish that are higher in omega-3s to begin with, including ocean-farmed Atlantic salmon and Chinook salmon, plus mackerel, which has 21% more of the two most important omega-3s (EPA and DHA) than even the most omega-3-rich salmon.

I have been told that the sugar substitute Splenda is unhealthy due to the chemicals used to process sugar into Splenda. Can you clarify?

Answer :  It’s true that Splenda is made using chlorine, which sounds scary; the sugar industry warns that you’re “actually eating chlorine” when consuming sucralose, the chemical sold as Splenda. Plain sugar is transformed into sucralose by substituting three chlorine atoms for hydrogen, creating a substance that is not digested by the body—so it’s effectively caloriefree— and that’s 600 times sweeter than sugar. (Packaged Splenda also contains dextrose and maltodextrin as bulking agents.) But there’s no evidence that the chlorine atoms in sucralose are any more dangerous than they are in, say, sodium chloride—ordinary salt. Before giving sucralose the OK, the US Food and Drug Administration reviewed more than 110 human and animal studies demonstrating its safety.

I am enclosing an article from a local newspaper warning people to avoid eating any fish ever (“Thinking Twice About Tuna” by Bruce Friedrich of the People for the Ethical Treatment of Animals, Palo Alto Daily News). I would like to know whether this very alarmist article has any basis in fact.

Answer :  The article in question warns about the dangers of mercury and other contamination in tuna and other fish, concluding that “Fish is anything but ‘health food.’“ While it’s wise to be wary of potential toxins in fish, the consensus of scientists who have examined the evidence—as opposed to taking an ethical stand, as PETA does, that “animals are not to eat”—is that fish is in fact one of the healthiest foods you can include in your diet. As reported in the January 2007 Healthletter, a 14-member Institute of Medicine (IOM) expert panel concluded that the rewards of eating fish outweigh the risks. “Confusion may have scared people out of eating something that is beneficial for them and maybe for their offspring,” according to Jose M. Ordovas, PhD, director of the Nutrition and Genomics Laboratory at Tufts’ Jean Mayer USDA Human Nutrition Center on Aging and a member of the panel. “People should not be scared about eating seafood.”

Almost simultaneously, an analysis of more than 200 previous studies strongly endorsed the cardiovascular benefits of fish consumption. The report, published in the Journal of the American Medical Association, concluded that the risks of mercury and other toxins in fish are “outweighed by potential benefits of fish intake and should have little impact on choices of fish consumption.” Harvard’s Dariush Mozaffarian, MD, DrPH, co-author of the report, maintains, “Seafood is likely the single most important food one can consume for good health.”

No wonder, then, that the American Heart Association and the latest federal dietary guidelines both recommend eating fish twice a week.

According to the IOM findings, only women who are or who may become pregnant or who are breast-feeding, along with children up to age 12, need to limit seafood consumption because of contamination risks. This group can still consume up to 12 ounces of fish a week, while avoiding large predatory fish such as shark, swordfish, tilefish or king mackerel. Others worried about contaminants should select a variety of seafood to minimize risk from any single source.

If you want to skip eating seafood for ethical reasons, that’s your choice. But there’s no scientific reason to eschew fish on the basis of health—indeed, just the opposite is true.

You mention “Body Mass Index” (BMI), but instead of explaining how to calculate it you refer to a Web site. How can I calculate BMI without a computer?

Answer :  You can calculate BMI without resorting to one of the many online calculators (such as www.nhlbisupport.com/ bmi), but you may want to at least have your own calculator handy. According to the Centers for Disease Control and Prevention, the official formula for calculating BMI using common US measurements is: Divide your weight in pounds by your height in inches squared; then multiply the result by a conversion factor of 703—that is, (weight/height2) x 703. So, for example, a 150-pound person who is 5-feet-5 (65 inches) would have a BMI of 24.96: 150 divided by 4,225 (65 times 65) equals 0.0355; times 703 equals 24.96. If you’ve mastered the metric system, the formula is a bit simpler: weight in kilograms divided by height in meters squared. In either case, you must multiply the height figure times itself first.

In your May “Ask Tufts Experts,” you compared the nutrition in white potatoes, sweet potatoes and yams. But I’m confused about the difference between sweet potatoes and yams?

Answer :  You’re not alone! According to the North Carolina Sweet Potato Commission, the confusion stems from the introduction of orange-fleshed sweet potatoes into the southern US. Producers wanted to differentiate them from the pale-fleshed sweet potatoes already familiar to consumers. So they adopted an English form of “nyami,” the African word for the starchy, edible root of the Dioscorea genus of plants. Despite that confus ing name, however, both the tan variety with creamy yellow insides and the more commonly eaten, more recently introduced “yam”—with copper skin and deep orange flesh—are botanically sweet potatoes. Both are from the genus Ipomoea, the morningglory family, and are native to the Americas (as is the white potato—though botanically also a different genus, again despite the name). True African Dioscorea “yams” are rarely sold in US markets; they are also called Chinese yams or Chinese potatoes (more confusion!). The US Department of Agriculture requires that the label “yam” always be accompanied by the term “sweet potato,” as in “yam sweet potato.”

To clarify our original answer, in terms of vitamin A, the orange-fleshed variety of sweet potatoes (sold as “yams”) are higher in beta carotene than the paler-fleshed type. (Thanks to reader and dietician Barbara Ashburn for her research assist on “yams.”)

Your Special Report on aspartame and high-fructose corn syrup (September Healthletter) made me wonder about ordinary table sugar. How does it compare to fructose in terms of calories? And if I want to cut calories but am still concerned about aspartame, what are my options?

Answer :  In fact, regular table sugar (sucrose) isn’t so different from high-fructose corn syrup (HFCS), which contains either 55% or 42% fructose plus other sugars, primarily glucose. Table sugar is 50% fructose and 50% glucose. Both table sugar and HFCS contain four calories per gram, so if you’re counting calories you should limit both sweeteners.

To satisfy your sweet tooth without calories or aspartame, the FDA has approved four other artificial sweeteners:

Saccharin: Some 200 to 700 times sweeter than sugar, saccharin was removed from the agency’s Generally Recognized As Safe (GRAS) list in 1972; the FDA proposed a ban in 1977. Concerns over bladder cancer in rats given high doses of saccharin were alleviated, however, by subsequent National Cancer Institute findings. Those showed that the bladder tumors were caused by a mechanism that doesn’t apply to humans, and that saccharin does not cause cancer in people. The National Toxicology Program determined in 2000 that saccharin should no longer be listed as a carcinogen. Saccharin is sold under brand names including Sweet’N Low, Sweet Twin and Necta Sweet.

Acesulfame-K: Some 200 times sweeter than sugar, with zero calories, acesulfame-k is sold under brands including Sunett and Sweet One. More than 90 studies have supported its safety.

Neotame: A whopping 7,000 to 13,000 times sweeter than sugar, neotame has zero calories. It’s been approved as a general-purpose sweetener in a variety of foods, and more than 100 studies have shown it to be safe.

Sucralose: Also the subject of controversy, sucralose, sold as Splenda, is 600 times sweeter than sugar. It adds no calories because it isn’t digested in the body. Sucralose is made by substituting three chlorine atoms for hydrogen in ordinary sugar, a technology that the sugar industry has used to raise concerns about sucralose. The FDA reviewed more than 110 human and animal studies demonstrating the safety of sucralose, however. And there’s nothing necessarily scary about ingesting chlorine atoms; half the atoms in ordinary table salt, after all, are chlorine.

In your June 2007 newsletter you reported the recommended AREDS antioxidants combination to reduce the risk of macular degeneration. It included copper. Recently, on a TV program, I heard a doctor warning against using copper as part of a multivitamin intake, stating that copper was bad for your health. It would be reassuring reading your opinion on this. If copper is to be used, in what amounts?

Answer :  Copper is an essential mineral with an established Recommended Dietary Allowance (RDA) of 900 micrograms (0.9 milligrams) per day for adults and a Tolerable Upper Intake Level (UL) of 10,000 micrograms (10 milligrams) daily. (The UL is the maximum daily intake of a nutrient that is likely to pose no risks of adverse health affects for almost all individuals.) According to Jeffrey Blumberg, PhD, director of the Antioxidants Research Laboratory at Tufts’ Jean Mayer USDA Human Nutrition Research Center on Aging, high levels of zinc may interfere with the absorption of copper. Since a high dose of zinc—80 milligrams, compared to the RDA of 9 milligrams daily for women and 11 for men—was used in the AREDS supplement, copper was added to the formula. In this case, the copper is not aimed at eye health but rather to offset the potential for impaired copper bioavailability caused by the high levels of zinc.

That’s not to say, however, that copper doesn’t have important health benefits. According to the USDA’s Agricultural Research Service (ARS), “Copper often is overlooked as an important nutrient when considering diets that promote cardiovascular health in humans.” One indication of the relationship between copper and heart health comes from the finding that copper concentrations in diseased hearts often are lower than the concentrations found in healthy hearts.

Another comes from recent research at the ARS’ Grand Forks Human Nutrition Research Center, showing that dietary copper may be beneficial even when the heart already is diseased. In the experiments, mice consuming a high-copper diet reversed a surgically induced enlargement of the heart and showed greatly reduced structural damage to the heart. More research will be needed to see if these findings can be extended to humans, however.

Adding copper-rich foods to the diet may be particularly important for women, according to ARS experts. Dietary surveys indicate that 10-25% of women have copper intakes lower than the RDA.

Foods that are high in copper content include shrimp, lobster, crab, whole grains, nuts, seeds, beans, lentils and mushrooms. It’s practically impossible to get an unsafe amount of copper from food alone; for example, a three-ounce serving of shrimp contains just 163 micrograms of copper. Even dietary supplements don’t approach the UL for copper: A typical multivitamin or “vision formula” supplement might contain 2,000 micrograms (2 milligrams) of copper, just one-fifth the limit of safety.

I enjoy Indian food very much and it appears very healthy, with many vegetables that are tasty and interesting. But most Indian recipes are made with clarified butter or “ghee.” I imagine this is not very beneficial from the point of view of fat and atherosclerosis, but I may be wrong. Could you explain and give your opinion?

Answer :  Ghee—“clarified” butter, with the milk solids removed—is made by heating unsalted butter to separate the milk solids from the pure butterfat. Although practitioners of Ayurvedic medicine in India claim that ghee has special health properties, some experts argue that the prevalence of ghee in Indian cuisine is actually a contributor to the high rates of heart disease in that country. In any case, Alice H. Lichtenstein, DSc, director of the Cardiovascular Nutrition Laboratory at Tufts’ Jean Mayer Human Nutrition Research Center on Aging (HNRCA), says that since ghee is butterfat, it’s high in saturated fat. “Substitute liquid vegetable oil,” she advises. “It may not taste quite the same, but given all the other seasonings it is a small price to pay for lowering your saturated fat intake. And, as always, go heavy on the vegetables when you are putting the dish together.”

I keep reading that adding milk to tea interferes with its antioxidant activity. How about soy milk?

Answer :  Jeffrey Blumberg, PhD, director of Tufts’ HNRCA Antioxidants Research Laboratory, replies, “I am unaware of any studies that have examined the effect of soy milk on the antioxidant activity of tea. However, the basic premise of this interaction is that the protein (mostly casein) in milk binds to the tea flavonoids, particularly the catechins, and thus inhibits their antioxidant capacity as well as bioavailability. As soy milk also contains substantial protein (albeit not casein), a similar reaction is plausible.” He cautions, though, that the evidence that cow milk does bind significantly to tea flavonoids and impairs their antioxidant activity and bioavailability is equivocal.

Is there any relationship between blood type and nutrition? Are certain foods detrimental to some blood types and excellent for other blood types?

Answer :  The notion that the four major blood types evolved in different environments and thus predispose people to different nutritional needs was popularized by naturopath Peter D’Adamo in a 1996 bestselling book, Eat Right 4 Your Type. According to D’Adamo, people with type-O blood, for instance, evolved as hunters and should eat plenty of red meat, while agrarian type-As should eat more grains. D’Adamo claimed to have collected “over 1,000 scientific articles on blood types and their correlations to disease, biochemistry, nutrition and anthropology.”

But a search of two leading nutrition journals, the Journal of Nutrition and the American Journal of Clinical Nutrition, going back more than 40 years finds only 14 citations even mentioning the words “blood type,” none of which have anything to do with matching diet to blood type. A search of the National Library of Medicine’s PubMed database for “blood type” and “diet” turns up only seven citations, two of which are articles debunking D’Adamo’s theory and none that support this notion. In short, the scientific evidence for this idea is slim to nonexistent.

“The truth is that there is no scientific evidence to support that dietary fad,” says José M. Ordovas, PhD, director of the Nutrition and Genomics Laboratory at Tufts’ Jean Mayer USDA Human Nutrition Research Center on Aging. “Moreover, I have not seen any serious attempt within the mainstream science to carry out any study to investigate this concept.”

Blood type actually has little to do with body chemistry or digestion. And even the classification of four blood types is only part of the story: Since pathologist Karl Landsteiner identified the A, AB, B and O groups early in the 1920s, some 200 different blood group substances have been identified and grouped within 19 different systems.

Most experts discount the idea that your blood type should dictate any departure from the basics of a healthy diet. “Telling people that they should eat more meat because they have type-O blood is irresponsible,” argued cardiologist and diet-book author Dean Ornish, MD, when Eat Right 4 Your Type was first published. The late Victor Herbert, MD, a physician at Mount Sinai Medical Center and frequent critic of alternative medicine, said the idea of linking blood type and diet is “pure horse manure. It has no relation to reality. The genes for blood type have nothing to do with the genes that handle the food we eat.”

Scientists such as those at Tufts’ Nutrition and Genomics Laboratory are investigating ways your genetic inheritance might influence your nutritional needs, metabolism, aging and propensity to obesity. But this research looks at genetic factors much more complex than simple blood-type grouping.

In your August newsletter it is stated that we should not fry fish. My wife says you are talking about battered fish or shrimp that is deep-fried, such as fish sticks or fast-food fish sandwiches. She says it’s OK to “fry” fish such as plain Tilapia in a tablespoon of olive oil in a skillet on the stove top. I say that your article means neither deep frying nor skillet frying should be done. Who’s right?

Answer :  You owe your wife a nice fish dinner (baked, not deep-fried). The research we cited refers specifically to commercially fried fish, mostly breaded and fried in hydrogenated fat, of the sort your wife has in mind. Alice H. Lichtenstein, DSC, director of the Cardiovascular Nutrition Laboratory at the Jean Mayer USDA Human Nutrition Center on Aging at Tufts, says, “If someone wants to fry at home that is fine, just as long as they use liquid vegetable oil and don’t need to be concerned about the extra calories. I frequently sauté onions in pan and then ‘fry’ salmon. I am not certain other people would call that frying but it looks like what your wife is thinking of. The advantage of my technique is you don’t heat the oven up and you have only one pan to clean up.”

In your July newsletter, you indicated that whole grain consists of bran, germ and endosperm. For years I have been purchasing wheat germ and wheat bran and using a heaping tablespoon of each in a liquid mixture at breakfast and dinner. From your article I gather that I am failing to consume a whole grain product. Is the endosperm essential? Do I need to change this consumption pattern?

Answer :  

Each part of a whole kernel of wheat brings something to the nutritional party. According to the Wheat Foods Council and the Consultative Group on International Agricultural Research, the bran (outer layer) contains the largest amount of fiber, though otherwise it has little nutritional value. The germ (inner part—essentially the embryo of the berry) is a rich source of trace minerals, unsaturated fats, B vitamins, antioxidants and phytochemicals. The germ has a nutty flavor and is oily, which causes it to turn rancid quickly. The endosperm (middle layer) contains mostly protein and carbohydrates along with small amounts of B vitamins, niacin and iron. The endosperm actually makes up the majority of the kernel, and is the primary source of many wheat flours.

When scientists have studied the health benefits of whole grains, much of their data has come from looking at people’s dietary patterns. Researchers have not looked separately at the health benefits of the individual components of wheat, so we don’t know whether consuming these components separately will have the same effect as eating whole grains.

Moreover, people who seek out wholegrain products are likely eating in other “heart-healthy” ways that reduce their risk of cardiovascular disease, notes Tufts expert Alice H. Lichtenstein. “Even though researchers try to correct for those factors, my feeling is it is the whole package, not just one component,” she adds.

Everyone is singing the praises of fish oil nowadays, but I read that it raises your LDL bad) cholesterol? Is that true? so, what is the alternative?

Answer :  Alice H. Lichtenstein, DSc, director of the Cardiovascular Nutrition Laboratory at Tufts’ Jean Mayer Human Nutrition Research Center on Aging, explains that fish is beneficial because it’s an excellent source of the omega-3 fatty acids EPA and DHA. (For more on the benefits of omega-3s—and why other dietary sources such as walnuts and flaxseeds aren’t an efficient way to get EPA/DHA—see the July Special Report.) Fish and fish oil raise LDL cholesterol only in some hypertriglyceridemic individuals—those with an unhealthy excess of triglycerides in the blood—who take two to four grams a day of fish oil. (That’s a lot of fish oil, by the way: A typical fish-oil supplement contains 300-500 milligrams of EPA/DHA, and manufacturers recommend one to three such capsules daily, for a total of no more than about one gram. A three-ounce serving of salmon, before cooking, contains a little less than a gram of total omega-3s.) Even in such cases, Lichtenstein explains, the person’s decrease in triglycerides and increase in “good” HDL cholesterol offset any potential adverse effects from the small increase in LDL. For most people, anyway, this is not an issue, so go ahead and eat fish! The American Heart Association and the latest federal dietary guidelines both recommend eating fish—especially the fatty, cold-water varieties like salmon highest in omega-3s—at least twice a week.

What is the recommend daily dose of folate? Is there an upper limit?

Answer :  According to the Institute of Medicine, which sets Dietary Reference Intakes (DRI), the recommended daily amount of folate for adult males is 400 micrograms. The recommendation is the same for adult females, except for during pregnancy, when it increases to 600 micrograms daily, and lactation, 500 micrograms. For comparison, a half-cup serving of spinach, a food relatively high in folate, has 29 micrograms. Much of our dietary folate comes from foods that have been supplemented with this nutrient— so, for example, a one-third-cup serving of Kellogg’s All Bran Buds contains 403 micrograms of folate, 101% of the recommended daily value.

The Tolerable Upper Intake Level (UL)— the maximum amount of a daily nutrient that’s likely to cause no adverse effects—for folate is 1,000 micrograms daily for adult men or women. In the case of folate, the UL applies to synthetic forms obtained from supplements, fortified foods, or a combination of the two.

At our local supermarkets a fish called “steelhead trout” is sold. The flesh is pinkish like salmon, not like trout. What exactly is this fish and is it a good source of omega-3?

Answer :  Steelhead trout (Oncorhynchus mykiss) is a rainbow trout that has spent part of its life in the sea. Also called “salmon trout” or “sea-run trout,” it’s a large, bluish fish that’s prized by sport fishermen. According to the Alaska Department of Fish and Game, “There are no major physical differences between rainbow and steelhead trout; however, the nature of their differing lifestyles has resulted in subtle differences in color, shape and general appearance.” All trout and salmon, along with chars, belong to the family Salmonidae, sometimes referred to as “salmonids.” Steelhead trout are actually similar to some Pacific salmon in their ecological needs and life cycles: Both are born in freshwater streams, then swim to the ocean after one to three years; like salmon, steelhead return to their native streams to spawn, but they don’t necessarily die after spawning, as salmon do.

Wild steelhead trout, like wild salmon, get the pinkish-orange color of their flesh from crustaceans and other colorful prey they consume. Farm-raised salmonids are naturally gray-fleshed; producers dye the flesh to make it look more appealing to consumers. Most steelhead trout available in supermarkets is farm-raised.

A 100-gram serving (about 3.5 ounces) of farm-raised steelhead, cooked by dry heat, provides 1.236 grams of omega-3 fatty acids. A similar portion of farm-raised Atlantic salmon contains 2.26 grams of omega-3s. Steelhead trout is high in protein (24.2 grams in 100 grams) and relatively low in calories (170), and is also a good source of niacin, vitamin B12, pantothenic acid and selenium.

In your April issue on “Eating for Endurance,” you state that plant proteins are incomplete proteins with the exception of soy protein. I thought quinoa supplied all the essential amino acids. Isn’t quinoa a complete protein grain?

Answer :  Actually, neither soy nor quinoa—which is technically a seed, but is cooked like a grain—is a “complete protein” in the sense of delivering as much of all essential amino acids as do animal options such as beef, milk or eggs. Quinoa and soy, as well as wheat, are very good protein sources and deliver at least some percentage of all the amino acids your body needs. But plant proteins, including these three, fall short of beef in their share of certain amino acids. Coupled with beans or another complementary protein source, however, quinoa delivers a complete package of protein. Quinoa also contains more iron than most grains, and provides some calcium, phosphorus, folate and B vitamins. No wonder the Incas called quinoa “the mother grain”!

Is there a chart of daily food allowances for people over 80 years old?

Answer :  We’ve received a number of questions along this line, wondering about dietary data specifically for older adults. If you have access to the Internet and the free Adobe Acrobat Reader software (available at www.adobe.com/products/acrobat/readstep2. html), you can view a complete chart of Dietary Reference Intakes (DRI) established by the Institute of Medicine at www.iom.edu/ File.aspx?ID=21372. This chart breaks out daily dietary needs by gender and age, including categories for males and females ages 70- plus. You can also go to the Web site for the new federal dietary pyramid at , enter your age, gender and typical exercise level, and receive a customized version of the pyramid, including a complete eating plan.

You’re correct in thinking that dietary needs change with age. Although the recommended intakes for many vitamins and nutrients are the same for all adults, the adult DRIs increase with age for vitamins including C, D, K and B6 as well as calcium. Your need for some minerals actually decreases with age—notably iron (for males after 18 and females after 50), chromium, phosphorus (after age 18), sodium and chloride. But don’t worry too much about the numbers—in general, if you eat a balanced, varied diet like that spelled out by MyPyramid, you’ll get most of the nutrients you need, whatever your age.

Does regular exercising enlarge one’s lipid particles (HDL, LDL and VLDL), which is supposed to be beneficial to one’s health?

Answer :  “The major determinant of VLDL, LDL and HDL particle size is the level of triglyceride in the blood,” replies Ernst J. Schaefer, MD, chief of the Lipid Metabolism Laboratory at Tufts’ Jean Mayer USDA Human Nutrition Research Center on Aging. “Regular exercise and weight loss if indicated can help lower triglyceride to less than 150 mg/dl. Below this level, most of LDL particles are type or large particles.”

I have seen many emails and Web postings about people getting sick from the artificial sweetener aspartame. I am a diet cola consumer, so I wonder: Is aspartame dangerous?

Answer :  The Internet is full of misinformation about aspartame, according to David Hattan, PhD, of the Food and Drug Administration’s (FDA) division of health effects evaluation. Hattan says there is no “credible evidence,” to support, for example, rumored links between aspartame and systemic lupus or multiple sclerosis. True, ingesting aspartame results in the production of substances that could be toxic at high doses: methanol, formaldehyde and formate. But the amounts are small—less methanol, for instance, than found in tomatoes or citrus juices.

The FDA does require products containing aspartame to be labeled for phenylalanine, an amino acid that can cause problems for people with a rare hereditary condition. Another amino acid in aspartame that’s the subject of Internet rumors, aspartic acid, could cause brain damage at extremely high doses. But the FDA calculates that most aspartame users consume only 4 to 7 percent of the safe maximum daily intake.

Other claims against aspartame, such as supposed links to seizures and birth defects, have failed to be supported by testing, even when lab animals ingested aspartame at doses far higher than humans would ever consume. The FDA says aspartame, sold under trade names such as NutraSweet and Equal, is one of the most thoroughly tested and studied food additives the agency has ever approved. More than 100 toxicological and clinical studies confirm that aspartame is safe for the general population.

I’ve read that calcium should be taken/ingested periodically during the day, as only a certain amount is absorbed at once. Please tell me if this is important and, if so, how much is advisable to take and at what intervals?

Answer :  Bess Dawson-Hughes, MD, professor of medicine at Tufts and chief of the Bone Metabolism Laboratory at the Jean Mayer USDA Human Nutrition Research Center on Aging, responds: “Calcium is better absorbed if taken in doses of 500 milligrams or less. So 1,000 milligrams as a supplement should be taken in doses of 500 milligrams twice daily.”

Is canned spinach just as good as fresh spinach to protect my vision?

Answer :  Scientists believe that eating lutein, a nutrient found in green vegetables such as spinach, kale and broccoli, may help prevent eyesight deterioration. It is believed that lutein protects against cataracts and agerelated macular degeneration (AMD), both of which cause loss of vision. According to Allen Taylor, PhD, director of the Laboratory for Nutrition and Vision Research at Tufts’ Jean Mayer USDA Human Nutrition Research Center on Aging, the lutein content of spinach is not damaged in the canning process. So, yes, canned spinach will be as beneficial for vision as fresh spinach.

Although leafy greens—spinach, kale, chard, turnip and mustard greens, collards, chicory, cress, radicchio, parsley and even dandelion greens—are by far the best sources of lutein, you can also add lutein to your diet by eating peas, summer squash, leeks and pasta made with spinach.

We always have a bounty of fresh fruit—more than we can eat before it goes bad. Is it possible to freeze fresh fruit without adding sugar?

Answer :  Healthletter recipe consultant Patsy Jamieson replies: “To freeze fresh fruit without sugar, peel and pit, if necessary, or rinse and pat dry. Slice or cut fruit into bite-sized pieces. Spread on a tray, cover and freeze until solid. Transfer to a plastic food storage bag, remove air from bag, seal and label. Freeze for up to eight months. To prevent peaches, bananas and mangos from turning brown, coat with lemon juice or an anti-browning product, such as Fruit-Fresh or Ever-Fresh.”

What’s the safe level of daily vitamin D? Is it different for older people? Also, I take fish-oil pills each day as recommended by my heart specialist, as well as a vitamin D supplement, and I’m worried that I may be getting too much vitamin D. How much vitamin D is found in fish-oil pills if any?

Answer :  The recommended intake of vitamin D—but not the safe limit—does increase with age: The Institute of Medicine has set the daily adequate intake for adults ages 19 to 50 at 200 IU of vitamin D, for ages 51 to 70 at 400 IU, and for those older than age 70 at 600 IU. Many experts, however, argue that those levels should be raised, and research has shown that 800 to 1,000 IU daily may be needed to obtain the full range of health benefits.

It is possible to get too much of a good thing, though: Vitamin D can be toxic at high levels of intake. Too much vitamin D can cause dangerous calcium deposits in organs, including the heart, and can damage the kidneys. The Institute of Medicine’s “Tolerable Upper Intake Level” (UL) for vitamin D is set at 2,000 IU daily for adults, regardless of age, although the lowest dose at which adverse effects have been registered is 3,800 IU. Given the modest amounts even in foods richest in vitamin D—98 IU in a cup of fortified milk, for example, and 360 IU in 3.5 ounces of cooked salmon—it’s highly unlikely you could ever eat your way to an overdose. Typical vitamin D supplements contain 400 to 800 IU in a single capsule, however, so take them judiciously.

The issue of vitamin D in fish oil actually more concerns cod liver oil, which mothers used to give their children to combat rickets (caused by a deficiency of vitamin D). A tablespoon of cod liver oil contains 1,360 IU, so it’s true that combining cod liver oil and vitamin D capsules could quickly exceed safe limits. Checking with two leading supplement manufacturers, however, confirms that fish-oil capsules contain levels of vitamin D too low to detect.

I have been hearing about cinnamon as a “cure” or at least a treatment for diabetes. As a patient with medically controlled type 2 diabetes, I am naturally interested. Anything to it?

Answer :  A 2003 study of 60 people with type 2 diabetes did find that intake of one to six grams of cinnamon daily improved blood glucose levels, as well as lipid factors (such as cholesterol) important to cardiovascular disease. Subsequent research on possible benefits for diabetics from the popular spice, however, have been disappointing. Most recently, two reviews of the scientific literature both came to similar negative conclusions: “Based on the currently available evidence, cinnamon should not be recommended for the improvement of glycemic control,” wrote a team of Dutch researchers in December 2007. And University of Connecticut experts in January 2008 concluded that cinnamon does not appear to improve a key measure of chronic blood-glucose levels, fasting blood glucose or lipids in patients with type 1 or type 2 diabetes. So, at least for now, it looks as though cinnamon belongs on the spice rack, not in the medicine cabinet.

I have been told that using olive oil for cooking causes the oil to hydrogenate and is therefore unhealthy. Would you please address this?

Answer :  

“Hydrogenation” means just what it sounds like—adding hydrogen to the molecules of a vegetable oil. The process uses hydrogen gas plus a metal catalyst, such as nickel. So unless you have a highly unusual kitchen, it’s not something that happens in the home. Merely cooking with olive oil or any other oil cannot hydrogenate it.

The concern about hydrogenated oils springs from research into trans fat, which has been found to increase LDL-cholesterol (the “bad” kind) without increasing “good” HDL-cholesterol levels. Tufts researchers have also found that trans fats tend to decrease the particle size of LDL-cholesterol—making them even more unhealthy by depositing more cholesterol in the arteries. While some trans fats occur naturally in animal products, by far the biggest dietary source is vegetable oil that has been hydrogenated. This chemical process turns liquid vegetable oils into solids at room temperature, such as stick margarine and shortening. These hydrogenated oils have been widely used in processed foods and baked goods and frying fast food. Many manufacturers are now phasing out hydrogenated oils, and the FDA will require trans fats to be identified on food labels as of next year.

Do you know anything about a substance called “714X” that has been used in the treatment of cancer? My cousin told me she heard something about it on TV. Where can I find out more about it and its use?

Answer :  

Also called “trimethylbicyclonitramineoheptane chloride,” 714X is named for the initials of its inventor, Gaston Naessens (G and N being the 7th and 14th letters of the alphabet), plus X, the 24th letter of the alphabet, for 1924, the year Naessens was born. That unorthodox nomenclature should give you a clue about the scientific standing of 714X. Naessens, who is French but has long worked in Quebec, claims his compound can cure not only cancer but also multiple sclerosis, fibromyalgia and other diseases. As long ago as 1967, however, the American Cancer Society investigated and found no evidence for those claims or for Naessens’ supposed scientific credentials. According to Quackwatch, which monitors dubious medical claims, no clinical trial and no reputable scientific journal has ever found that 714X is effective against any health condition, including cancer. In 1990, the Canadian Health Protection Branch concluded, “No scientific evidence has been provided to support any claims made for the drug” and “deplored” the use of 714X to treat cancer and AIDS. In the US, the Food and Drug Administration has successfully prosecuted those importing 714X.

As tempting as it may be to try such supposed “wonder drugs” against diseases as frightening as cancer, you risk becoming a victim of fraud as well. For the most up-todate patient information on cancer treatment and a set of interactive treatment-decision tools, see the American Cancer Society’s Web site at www.cancer.org.

I understand that Concord grapes are high in nutritional value. Because I don’t see this variety in local super markets, do other red grapes have similar nutritional value?

Answer :  In general, according to James A. Joseph, PhD, chief of the Neuroscience Laboratory at Tufts’ Jean Mayer USDA Human Nutrition Research Center on Aging, grapes with the most color have the highest degree of antioxidants. Anthocyanins, the pigments that give red and purple grapes their color, have been associated with a variety of possible health benefits; they are not unique to Concord grapes. Some white grapes, however, are rich in proanthocyanidins, another type of antioxidant found in grape seeds and skin that may have health benefits.

Which is “fresher”— vegetables canned soon after harvesting, frozen or so-called “fresh” as pawed over by the public or in plastic?

Answer :  There’s no real scientific measure of “freshness,” but if you mean vegetables that are closest in nutrient content to freshly picked vegetables, the best bet is probably frozen produce. Alice H. Lichtenstein, DSc, Stanley N. Gershoff professor of nutrition science and policy at Tufts’ Friedman School, says, “For the most part, frozen vegetables are processed close to the point of harvesting, and, unless thawed and refrozen prior to sale, should retain most of their nutrients. Fresh vegetables —more so than frozen or canned— can vary in quality, depending on when they were picked relative to when they are available for purchase and the conditions under which they were stored, the length of time stored and the conditions under which they are displayed.

Canned vegetables are different. They are cooked and hence, not comparable to frozen or fresh vegetables. Canned vegetables are lower in heat-labile nutrients— those that are unstable when heated, as in the canning process.” Many canned vegetables also have added salt; if you do opt for canned, make sure to look for those that are low in sodium. Of course, it is also important how the vegetables are stored and prepared once you get them home from the market: Minimize excessive heat and cooking fluid unless it is going to be consumed, such as in soups.

As a vegetarian, I am interested in the combination of fruits and vegetables that will provide a complete set of essential amino acids in sufficient quantities. Can you help?

Answer :  Jeanne P. Goldberg, PhD, director of the Center on Nutrition Communication and the Nutrition Communication Program at Tufts’ Friedman School, answers, “This is really not difficult. In general, vegetables and grains are better sources of protein than fruits. Single groups of plant foods typically do not contain all of the essential amino acids in the balance that the body needs them, but if you eat a variety you will get all you need. For example, legumes are low in methionine, a sulfur-containing amino acid, but grains have quite a bit. On the other hand, grains are limited in lysine, which the legumes do have. By eating rice and beans together, the amino acid pattern of each is complemented. That approach, eating different vegetable foods together, serves to insure that people on vegetarian diets get all of the essential amino acids they need.”

Is it safe to eat the mold that forms on cheese? I tend to throw it out, but wonder if there are cheeses that have desirable molds.

Answer :  AIt’s important to differentiate between molds used to make certain cheeses and molds that form later in your refrigerator. Blue-veined cheeses such as Roquefort, blue, Gorgonzola and Stilton are created by introducing mold spores, while cheeses such as Brie and Camembert have white surface molds. The molds used to manufacture these cheeses are safe to eat, according to the USDA Food Safety and Inspection Service (FSIS). But when such cheeses develop molds not part of the manufacturing process, they should be discarded (soft cheeses) or the mold and at least an inch around it should be cut away (hard cheeses). Other hard cheeses can be similarly trimmed and then used. All soft cheeses such as cottage cheese, cream cheese, Neufchatel and chevre, as well as crumbled, sliced and shredded cheeses, should be discarded if they develop mold.

Why throw away even the “good part” of such cheeses? The FSIS warns, “Foods with high moisture content can be contaminated below the surface. Shredded, sliced or crumbled cheese can be contaminated by the cutting instrument. Moldy soft cheese can also have bacteria growing along with the mold.” Hard cheeses can be rescued, on the other hand, because mold generally cannot penetrate deep into such products.

What’s the difference between whole-wheat pastry flour and regular whole-wheat flour?

Answer :  Whole-wheat pastry flour is milled from a soft variety of wheat, which has less gluten-forming potential than regular whole-wheat flour, and is therefore an excellent choice for tender baked goods. White whole-wheat flour is a special variety of hard wheat. Although it has a lighter color and sweeter flavor than regular whole-wheat flour, this flour contains all the benefits of whole-grain flour because it is milled from the entire wheat berry. Both types of flour are available in natural foods sections of supermarkets or through Web sources, such as kingarthurflour.com or bobsredmill.com. Store all whole-wheat flours in an airtight container or bag on the refrigerator or freezer. For an example of using either type of flour, see our Wholesome Gingerbread Cookies recipe below.

I usually agree with most of your articles, but I think you dropped the ball on your “51 Healthy Foods” (August) concerning peanut butter. You did not specify the peanut butter should be “natural.” Most others have hydrogenated trans fat and you know that is harmful.

Answer :  According to the US Department of Agriculture’s Agricultural Research Service (ARS), “Recurring rumors that commercial peanut butters contain trans fats… have no basis in fact.” True, small amounts of hydrogenated vegetable oils are added to commercial peanut butters—1%-2% of total weight—to keep the peanut oil from separating out. And the hydrogenation process can lead to the formation of trans fatty acids, which increase the risk of cardiovascular disease. But ARS testing of 11 brands of peanut butter, including major store brands and “natural” varieties, found no detectable trans fats in any of the samples. It’s expected that under new FDA labeling guidelines, all peanut butter will declare zero trans fat on the label. The tested peanut butters did have oleic acid, from 19%-27% by weight, a monosaturated fat believed to have beneficial cardiovascular effects.

In your list of “51 Healthy Foods,” you list carrots but do not say cooked or raw. It is my impression that the human system cannot digest raw carrots because the cellulose walls are resistant. Is this correct?

Answer :  While you can get nutrients and fiber from raw carrots, it’s true that one important nutrient—beta-carotene, which the body turns into vitamin A—is tightly bound to the protein in plants. A 2003 study at the Hebrew University of Jerusalem, published in the European Journal of Nutrition, concluded, “Significantly more beta-carotene was absorbed from meals containing cooked, pureed carrots than from meals containing the raw vegetable.” Research at the University of Arkansas found similar results; levels of beta-carotene and other antioxidants were even higher when the carrots weren’t peeled before pureeing and cooking.

For the lactose intolerant, does soy milk offer as much calcium benefit as cow’s milk?

Answer :  Soy milk is not a good natural source of calcium, but many brands of soy milk are fortified with calcium. Fortified soy milk typically has 200-400 milligrams of calcium per cup, which would provide 20%-40% of your RDA of calcium. For a chart comparing the calcium in various brands, see www.soyfoods.com/nutrition/ CalciumChart.html.

I make smoothies using only fresh squeezed OJ, yogurt and fresh or frozen fruit (mostly bananas and berries). Is the fiber in the fruit lost by blending them into the smoothie? What about other vitamins and minerals?

Answer :  

Not to worry, says Alice H. Lichtenstein, DSc, Gershoff Professor of Nutrition Science and Policy at Tufts’ Friedman School. You’re losing some fiber from the orange by squeezing out the juice and discarding the rest. Otherwise, however, all the fiber should remain, even after combining into a smoothie, and the fruits’ vitamins and minerals should be intact. Heating can destroy some nutrients, but not blending. (We trust, by the way, that you’re using low- or non-fat yogurt in that smoothie?)

Is there a difference in the effect on the body between natural (l-alpha tocopherol) and synthetic (d,ltocopherol) vitamin E?

Answer :  

Vitamin E (as alpha-tocopherol) can exist in two configurations, like a right and left hand (the d and l forms, respectively), explains Jeffrey B. Blumberg, PhD, chief of the Antioxidants Research Laboratory and Senior Scientist at Tufts’ Jean Mayer USDA Human Nutrition Research Center on Aging. Dietary vitamin E is always found as the l form while synthetic vitamin E is generally an equal mixture of the d and l forms. A vitamin E binding protein in the liver transfers the l form into lipoproteins for transport throughout the body and discriminates against the d form such that it is rapidly excreted. Thus, milligram for milligram, the natural dietary l form is about twice as potent as the d form that’s mixed into synthetic vitamin E. This difference is partly compensated for, however, by the way International Units (IU) are used to measure vitamin E: One IU of vitamin E contains 1.0 milligram of the d,l mixture, but it takes just 0.74 mg of the l form to equal 1 IU.

Can you compare the nutritional value of sweet potatoes/ yams with white Idaho baking potatoes? What about fiber content? Sweet potatoes seem to contain more fibrous material, but such impressions can be misleading.

Answer :  Sweet potatoes, yams (technically a different vegetable) and white potatoes all have their nutritional pluses, but you’re correct in thinking that sweet potatoes outdo their white-fleshed cousins in terms of dietary fiber. Exact numbers vary depending on variety, but generally a cup of diced, peeled sweet potato contains 4 grams of fiber—nearly double the 1.8 grams in the same amount of peeled white potato (3 grams if you eat the peel). Yams provide the most fiber of all, with 6.2 grams per cup of peeled, diced yams.

Calorie and protein counts are comparable. As you might guess by their orange color, sweet potatoes contain a whopping amount of vitamin A—almost 19,000 IU per cup, or nearly four times the Daily Value. Yams have only a fraction as much vitamin A—about 200 IU—and regular potatoes, none at all. White potatoes and yams do contain more vitamin C than sweet potatoes, though. Yams provide the most calcium, potassium and folate.

Correction: Several sharp-eyed readers wondered about our reference to “milligrams” of vitamin D in an article on page 8 of the February 2006 Healthletter. Vitamin D, of course, is measured in International Units (IU), which is what the article should have said.

I understand how to identify trans fats as “partially hydrogenated.” But I sometimes see “fully hydrogenated” —for example, on Reduced Fat Jif Peanut Butter. Can you please explain what “fully hydrogenated” means and what, if any, impact it has on our health?

Answer :  To understand the difference between “partially” and “fully hydrogenated” oils, you’ll need a short chemistry lesson—bear with us! In saturated fats, all the positions for hydrogen on the carbon atoms are filled. Monounsaturated fats have one pair of carbon atoms per chain that are connected to each other instead of to hydrogen atoms this carbon-carbon bond is thus “unsaturated”); so oleic acid, a monounsaturated fatty acid, which has 18 carbon atoms per chain, is denoted as 18:1. Polyunsaturated fats have more than one such carbon-carbon bond; linoleic acid, for example, is 18:2, meaning it has two “unsaturated” bonds in a chain of 18.

When oils get “hydrogenated,” all of these unsaturated bonds are catalytically converted to saturated bonds. In “partially hydrogenated” fat, some of the unsaturated bonds remain, but their geometry is changed to a “trans” configuration that lets the molecules lie parallel to each other. These more densely packed “trans fats” are thus solid at room temperature and handy for restaurant and bakery use.

Still with us? OK. When oils are “fully hydrogenated,” all their bonds get changed to hydrogen-carbon and there are no more “trans” molecules. Since most vegetable oil is primarily 18:2 (polyunsaturated), you end up with stearic acid (18:0), a saturated fatty acid. The good news is that, in the body, stearic acid does not have the same effect, for the most part, as other, less-healthy saturated fatty acids because it can get metabolized to oleic acid (18:1)—a healthier monounsaturated fat. Alice H. Lichtenstein, DSc, director of the Cardiovascular Nutrition Laboratory at Tufts’ Jean Mayer USDA Human Nutrition Research Center on Aging, concludes, “Hence, fully hydrogenating is one apparently good approach to avoiding trans fats while changing the physical form of the oil.”

The new federal dietary guidelines call for at least two servings of fish a week. At this time of year, the only fish available in my grocery store is farm-raised. I have also read that you should limit your consumption of farm-raised fish to two times a month. What should I do?

Answer :  

The new dietary guidelines don’t actually set a recommended serving amount for fish, but do note, “Evidence suggests that consuming approximately two servings of fish per week (approximately eight ounces total) may reduce the risk of mortality from coronary heart disease and that consuming EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) may reduce the risk of mortality from cardiovascular disease in people who have already experienced a cardiac event.” EPA and DHA are omega-3 fatty acids found in fish and shellfish. The American Heart Association does specifically recommend consuming fish twice a week.

The FDA has not issued any recommended limits on consumption of farmraised fish, though there are certain FDA recommended limits, specifically for pregnant women and children, to avoid mercury in fish. Concern about farm-raised salmon arose after a study by the Environmental Working Group found polychlorinated biphenyls (PCBs), which the Environmental Protection Agency (EPA) calls “a probable human carcinogen,” in 70 percent of such fish they bought at supermarkets.

But that study tested only 10 salmon fillets. Mark Woodin, PhD, a Tufts epidemiologist, has noted that while farm-raised salmon probably does have higher levels of PCBs than wild salmon, it’s very difficult to say just how toxic they might be. The EPA’s limits on PCBs are stricter than the FDA’s, but are based on the amount of PCBs thought to be capable of causing one additional cancer case in 100,000 people over a 70-year lifetime.

You have to balance risks and benefits, advises Alice Lichtenstein, Gershoff Professor at Tufts’ Friedman School of Nutrition Science and Policy. “The risk of developing cardiovascular disease (CVD) is high; it is the leading cause of death and disability in the US, and half of women in the US will die of CVD. Other than the special issue of pregnant women and children, the risk of adverse effects from contaminants in fish is extremely low, theoretical at this point.”

If you’re still wary, try canned tuna and salmon, which usually use wild fish because it’s firmer. All year-round, many supermarkets offer high-quality frozen fish that may include wild varieties.

I recently read that one shouldn’t microwave food in plastic containers because carcinogens are released into the food. Does this apply to all plastic containers, even those specifically designed for microwaving?

Answer :  

The supposed risks of carcinogens leaching from plastic into food when microwaved have reached the status of urban legend. The US Food and Drug Administration (FDA) has tried to reassure the public, noting that “the FDA carefully reviews the substances used to make plastics designed for food use.” Yes, says FDA consumer-safety official Edward Machuga, PhD, substances used to make plastics can leach into food. “But as part of the approval process, the FDA considers the amount of a substance expected to migrate into food and the toxicological concerns about the particular chemical.” As long as you use plastics as intended—don’t microwave re